Hickman JA - Search Results

1

Induction of apoptosis in HL-60 leukemia and B16 melanoma cells by the acronycine derivative S23906-1.

Kluza J, Lansiaux A, Wattez N, Hildebrand MP, Léonce S, Pierré A, Hickman JA, Bailly C. Kluza J, et al. Among authors: hickman ja. Biochem Pharmacol. 2002 Apr 15;63(8):1443-52. doi: 10.1016/s0006-2952(02)00899-7. Biochem Pharmacol. 2002. PMID: 11996885

2

Alkylation of guanine in DNA by S23906-1, a novel potent antitumor compound derived from the plant alkaloid acronycine.

David-Cordonnier MH, Laine W, Lansiaux A, Kouach M, Briand G, Pierré A, Hickman JA, Bailly C. David-Cordonnier MH, et al. Among authors: hickman ja. Biochemistry. 2002 Aug 6;41(31):9911-20. doi: 10.1021/bi020226+. Biochemistry. 2002. PMID: 12146956

3

Acronycine derivatives as promising antitumor agents.

Guilbaud N, Léonce S, Tillequin F, Koch M, Hickman JA, Pierré A. Guilbaud N, et al. Among authors: hickman ja. Anticancer Drugs. 2002 Jun;13(5):445-9. doi: 10.1097/00001813-200206000-00002. Anticancer Drugs. 2002. PMID: 12045455 Review.

4

Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: unique consequences of a novel DNA-bonding mechanism.

David-Cordonnier MH, Laine W, Lansiaux A, Rosu F, Colson P, de Pauw E, Michel S, Tillequin F, Koch M, Hickman JA, Pierré A, Bailly C. David-Cordonnier MH, et al. Among authors: hickman ja. Mol Cancer Ther. 2005 Jan;4(1):71-80. Mol Cancer Ther. 2005. PMID: 15657355

5

Novel stable camptothecin derivatives replacing the E-ring lactone by a ketone function are potent inhibitors of topoisomerase I and promising antitumor drugs.

Lansiaux A, Léonce S, Kraus-Berthier L, Bal-Mahieu C, Mazinghien R, Didier S, David-Cordonnier MH, Hautefaye P, Lavielle G, Bailly C, Hickman JA, Pierré A. Lansiaux A, et al. Among authors: hickman ja. Mol Pharmacol. 2007 Aug;72(2):311-9. doi: 10.1124/mol.107.034637. Epub 2007 May 9. Mol Pharmacol. 2007. PMID: 17494837

6

Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.

Léonce S, Pérez V, Lambel S, Peyroulan D, Tillequin F, Michel S, Koch M, Pfeiffer B, Atassi G, Hickman JA, Pierré A. Léonce S, et al. Among authors: hickman ja. Mol Pharmacol. 2001 Dec;60(6):1383-91. doi: 10.1124/mol.60.6.1383. Mol Pharmacol. 2001. PMID: 11723246

7

Structure-activity relationships and mechanism of action of antitumor benzo[b]pyrano[3,2-h]acridin-7-one acronycine analogues.

Thi Mai HD, Gaslonde T, Michel S, Tillequin F, Koch M, Bongui JB, Elomri A, Seguin E, Pfeiffer B, Renard P, David-Cordonnier MH, Laine W, Bailly C, Kraus-Berthier L, Léonce S, Hickman JA, Pierré A. Thi Mai HD, et al. Among authors: hickman ja. J Med Chem. 2003 Jul 3;46(14):3072-82. doi: 10.1021/jm030790y. J Med Chem. 2003. PMID: 12825945

8

An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells.

Cahuzac N, Studény A, Marshall K, Versteege I, Wetenhall K, Pfeiffer B, Léonce S, Hickman JA, Pierré A, Golsteyn RM. Cahuzac N, et al. Among authors: hickman ja. Cancer Lett. 2010 Mar 28;289(2):178-87. doi: 10.1016/j.canlet.2009.08.014. Epub 2009 Sep 15. Cancer Lett. 2010. PMID: 19758748

9

Synthesis and pharmacological evaluation of novel non-lactone analogues of camptothecin.

Hautefaye P, Cimetière B, Pierré A, Léonce S, Hickman J, Laine W, Bailly C, Lavielle G. Hautefaye P, et al. Bioorg Med Chem Lett. 2003 Aug 18;13(16):2731-5. doi: 10.1016/s0960-894x(03)00534-1. Bioorg Med Chem Lett. 2003. PMID: 12873503

10

Synthesis and biological activities of isogranulatimide analogues.

Hugon B, Anizon F, Bailly C, Golsteyn RM, Pierré A, Léonce S, Hickman J, Pfeiffer B, Prudhomme M. Hugon B, et al. Bioorg Med Chem. 2007 Sep 1;15(17):5965-80. doi: 10.1016/j.bmc.2007.05.073. Epub 2007 Jun 7. Bioorg Med Chem. 2007. PMID: 17582773

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