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A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.
Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G. Corallino S, et al. Among authors: frittoli e. Nat Commun. 2018 Apr 16;9(1):1475. doi: 10.1038/s41467-018-03571-8. Nat Commun. 2018. PMID: 29662076 Free PMC article.
An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine.
Scita G, Tenca P, Areces LB, Tocchetti A, Frittoli E, Giardina G, Ponzanelli I, Sini P, Innocenti M, Di Fiore PP. Scita G, et al. Among authors: frittoli e. J Cell Biol. 2001 Sep 3;154(5):1031-44. doi: 10.1083/jcb.200103146. Epub 2001 Aug 27. J Cell Biol. 2001. PMID: 11524436 Free PMC article.
Signaling from Ras to Rac and beyond: not just a matter of GEFs.
Scita G, Tenca P, Frittoli E, Tocchetti A, Innocenti M, Giardina G, Di Fiore PP. Scita G, et al. Among authors: frittoli e. EMBO J. 2000 Jun 1;19(11):2393-8. doi: 10.1093/emboj/19.11.2393. EMBO J. 2000. PMID: 10835338 Free PMC article. Review.
Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.
Innocenti M, Tenca P, Frittoli E, Faretta M, Tocchetti A, Di Fiore PP, Scita G. Innocenti M, et al. Among authors: frittoli e. J Cell Biol. 2002 Jan 7;156(1):125-36. doi: 10.1083/jcb.200108035. Epub 2002 Jan 3. J Cell Biol. 2002. PMID: 11777939 Free PMC article.
Abi1 regulates the activity of N-WASP and WAVE in distinct actin-based processes.
Innocenti M, Gerboth S, Rottner K, Lai FP, Hertzog M, Stradal TE, Frittoli E, Didry D, Polo S, Disanza A, Benesch S, Di Fiore PP, Carlier MF, Scita G. Innocenti M, et al. Among authors: frittoli e. Nat Cell Biol. 2005 Oct;7(10):969-76. doi: 10.1038/ncb1304. Epub 2005 Sep 11. Nat Cell Biol. 2005. PMID: 16155590
61 results