Matsui T - Search Results

1

Highly potent inhibitors of TNF-alpha production. Part 2: identification of drug candidates.

Matsui T, Kondo T, Nishita Y, Itadani S, Tsuruta H, Fujita S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Bioorg Med Chem Lett. 2002 Mar 25;12(6):907-10. doi: 10.1016/s0960-894x(02)00037-9. Bioorg Med Chem Lett. 2002. PMID: 11958991

2

Highly potent inhibitors of TNF-alpha production. Part 1: Discovery of chemical leads.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Bioorg Med Chem Lett. 2002 Mar 25;12(6):903-5. doi: 10.1016/s0960-894x(02)00036-7. Bioorg Med Chem Lett. 2002. PMID: 11958990

3

Highly potent inhibitors of TNF-alpha production. Part I: discovery of new chemical leads and their structure-activity relationships.

Matsui T, Kondo T, Nishita Y, Itadani S, Nakatani S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Terai K, Kamoshima W, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Bioorg Med Chem. 2002 Dec;10(12):3757-86. doi: 10.1016/s0968-0896(02)00381-4. Bioorg Med Chem. 2002. PMID: 12413832

4

Highly potent inhibitors of TNF-alpha production. Part II: metabolic stabilization of a newly found chemical lead and conformational analysis of an active diastereoisomer.

Matsui T, Kondo T, Nishita Y, Itadani S, Tsuruta H, Fujita S, Omawari N, Sakai M, Nakazawa S, Ogata A, Mori H, Kamoshima W, Terai K, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Bioorg Med Chem. 2002 Dec;10(12):3787-805. doi: 10.1016/s0968-0896(02)00380-2. Bioorg Med Chem. 2002. PMID: 12413833

5

Discovery of novel phosphonic acid derivatives as new chemical leads for inhibitors of TNF-alpha production.

Matsui T, Takahashi S, Matsunaga N, Nakamura K, Omawari N, Sakai M, Kamoshima W, Terai K, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Bioorg Med Chem. 2002 Dec;10(12):3807-15. doi: 10.1016/s0968-0896(02)00343-7. Bioorg Med Chem. 2002. PMID: 12413834

6

Synthesis, further biological evaluation and pharmacodynamics of newly discovered inhibitors of TNF-alpha production.

Matsui T, Kondo T, Nakatani S, Omawari N, Sakai M, Mori H, Ogata A, Kato J, Ohno H, Obata T, Nakai H, Toda M. Matsui T, et al. Bioorg Med Chem. 2003 Sep 1;11(18):3937-43. doi: 10.1016/s0968-0896(03)00409-7. Bioorg Med Chem. 2003. PMID: 12927854

7

Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists.

Naganawa A, Matsui T, Ima M, Yoshida K, Tsuruta H, Yamamoto S, Yamamoto H, Okada H, Maruyama T, Nakai H, Kondo K, Toda M. Naganawa A, et al. Among authors: matsui t. Bioorg Med Chem. 2006 Dec 1;14(23):7774-89. doi: 10.1016/j.bmc.2006.08.001. Epub 2006 Aug 22. Bioorg Med Chem. 2006. PMID: 16931028

8

Discovery of heteroaryl sulfonamides as new EP1 receptor selective antagonists.

Naganawa A, Matsui T, Saito T, Ima M, Tatsumi T, Yamamoto S, Murota M, Yamamoto H, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M. Naganawa A, et al. Among authors: matsui t. Bioorg Med Chem. 2006 Oct 1;14(19):6628-39. doi: 10.1016/j.bmc.2006.05.076. Epub 2006 Jun 19. Bioorg Med Chem. 2006. PMID: 16784865

9

Further optimization of sulfonamide analogs as EP1 receptor antagonists: synthesis and evaluation of bioisosteres for the carboxylic acid group.

Naganawa A, Matsui T, Ima M, Saito T, Murota M, Aratani Y, Kijima H, Yamamoto H, Maruyama T, Ohuchida S, Nakai H, Toda M. Naganawa A, et al. Among authors: matsui t. Bioorg Med Chem. 2006 Nov 1;14(21):7121-37. doi: 10.1016/j.bmc.2006.06.067. Epub 2006 Aug 1. Bioorg Med Chem. 2006. PMID: 16879970

10

6,7-Dihydro-5H-cyclopenta[d]pyrazolo[1,5-a]pyrimidines and their derivatives as novel corticotropin-releasing factor 1 receptor antagonists.

Saito T, Obitsu T, Kondo T, Matsui T, Nagao Y, Kusumi K, Matsumura N, Ueno S, Kishi A, Katsumata S, Kagamiishi Y, Nakai H, Toda M. Saito T, et al. Among authors: matsui t. Bioorg Med Chem. 2011 Sep 15;19(18):5432-45. doi: 10.1016/j.bmc.2011.07.055. Epub 2011 Jul 31. Bioorg Med Chem. 2011. PMID: 21865047

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