Hruby DE - Search Results

1

Analysis of factors affecting surface expression and immunogenicity of recombinant proteins expressed by gram-positive commensal vectors.

Bolken TC, Franke CA, Jones KF, Bell RH, Swanson RM, King DS, Fischetti VA, Hruby DE. Bolken TC, et al. Among authors: hruby de. Infect Immun. 2002 May;70(5):2487-91. doi: 10.1128/IAI.70.5.2487-2491.2002. Infect Immun. 2002. PMID: 11953386 Free PMC article.

2

Biological consequences of antigen and cytokine co-expression by recombinant Streptococcus gordonii vaccine vectors.

Byrd CM, Bolken TC, Jones KF, Warren TK, Vella AT, McDonald J, King D, Blackwood Z, Hruby DE. Byrd CM, et al. Among authors: hruby de. Vaccine. 2002 May 22;20(17-18):2197-205. doi: 10.1016/s0264-410x(02)00144-5. Vaccine. 2002. PMID: 12009273

3

Development of PLEX, a plasmid-based expression system for production of heterologous gene products by the gram-positive bacteria Streptococcus gordonii.

Warren TK, Lund SA, Jones KF, Hruby DE. Warren TK, et al. Among authors: hruby de. Protein Expr Purif. 2005 Apr;40(2):319-26. doi: 10.1016/j.pep.2004.10.019. Protein Expr Purif. 2005. PMID: 15766873

4

Development of a radioactive protein A-based assay for analysis of surface protein expression in gram-positive bacteria.

Coyle TC, Franke CA, Hruby DE. Coyle TC, et al. Among authors: hruby de. Appl Environ Microbiol. 1997 Jun;63(6):2477-80. doi: 10.1128/aem.63.6.2477-2480.1997. Appl Environ Microbiol. 1997. PMID: 9172373 Free PMC article.

5

Expression of active monomeric and dimeric nuclease A from the gram-positive Streptococcus gordonii surface protein expression system.

Dutton EK, Ottum SA, Bolken TC, Franke CA, Hruby DE. Dutton EK, et al. Among authors: hruby de. Protein Expr Purif. 2000 Jun;19(1):158-72. doi: 10.1006/prep.2000.1223. Protein Expr Purif. 2000. PMID: 10833403

6

Expression and purification of histidine-tagged proteins from the gram-positive Streptococcus gordonii SPEX system.

Myscofski DM, Dutton EK, Bolken TC, Franke CA, Hruby DE. Myscofski DM, et al. Among authors: hruby de. Protein Expr Purif. 2000 Oct;20(1):112-23. doi: 10.1006/prep.2000.1275. Protein Expr Purif. 2000. PMID: 11035959

7

Inactivation of the srtA gene in Streptococcus gordonii inhibits cell wall anchoring of surface proteins and decreases in vitro and in vivo adhesion.

Bolken TC, Franke CA, Jones KF, Zeller GO, Jones CH, Dutton EK, Hruby DE. Bolken TC, et al. Among authors: hruby de. Infect Immun. 2001 Jan;69(1):75-80. doi: 10.1128/IAI.69.1.75-80.2001. Infect Immun. 2001. PMID: 11119491 Free PMC article.

8

Identification of an intragenic integration site for foreign gene expression in recombinant Streptococcus gordonii strains.

Bolken TC, Franke CA, Zeller GO, Hruby DE. Bolken TC, et al. Among authors: hruby de. Appl Microbiol Biotechnol. 2001 Mar;55(2):192-7. doi: 10.1007/s002530000519. Appl Microbiol Biotechnol. 2001. PMID: 11330713

9

Conserved DegP protease in gram-positive bacteria is essential for thermal and oxidative tolerance and full virulence in Streptococcus pyogenes.

Jones CH, Bolken TC, Jones KF, Zeller GO, Hruby DE. Jones CH, et al. Among authors: hruby de. Infect Immun. 2001 Sep;69(9):5538-45. doi: 10.1128/IAI.69.9.5538-5545.2001. Infect Immun. 2001. PMID: 11500427 Free PMC article.

10

Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccine.

Kotloff KL, Wasserman SS, Jones KF, Livio S, Hruby DE, Franke CA, Fischetti VA. Kotloff KL, et al. Among authors: hruby de. Infect Immun. 2005 Apr;73(4):2360-6. doi: 10.1128/IAI.73.4.2360-2366.2005. Infect Immun. 2005. PMID: 15784582 Free PMC article. Clinical Trial.

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