Baillie TA - Search Results

1

Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization.

Prueksaritanont T, Subramanian R, Fang X, Ma B, Qiu Y, Lin JH, Pearson PG, Baillie TA. Prueksaritanont T, et al. Among authors: baillie ta. Drug Metab Dispos. 2002 May;30(5):505-12. doi: 10.1124/dmd.30.5.505. Drug Metab Dispos. 2002. PMID: 11950779

2

Biotransformation of methyl isocyanate in the rat. Evidence for glutathione conjugation as a major pathway of metabolism and implications for isocyanate-mediated toxicities.

Slatter JG, Rashed MS, Pearson PG, Han DH, Baillie TA. Slatter JG, et al. Among authors: baillie ta. Chem Res Toxicol. 1991 Mar-Apr;4(2):157-61. doi: 10.1021/tx00020a006. Chem Res Toxicol. 1991. PMID: 1782345

3

S-(N-methylcarbamoyl)glutathione: a reactive S-linked metabolite of methyl isocyanate.

Pearson PG, Slatter JG, Rashed MS, Han DH, Grillo MP, Baillie TA. Pearson PG, et al. Among authors: baillie ta. Biochem Biophys Res Commun. 1990 Jan 15;166(1):245-50. doi: 10.1016/0006-291x(90)91937-n. Biochem Biophys Res Commun. 1990. PMID: 2302207

4

The use of mass spectrometry in the study of chemically-reactive drug metabolites. Application of MS/MS and LC/MS to the analysis of glutathione- and related S-linked conjugates of N-methylformamide.

Baillie TA, Pearson PG, Rashed MS, Howald WN. Baillie TA, et al. J Pharm Biomed Anal. 1989;7(12):1351-60. doi: 10.1016/0731-7085(89)80140-2. J Pharm Biomed Anal. 1989. PMID: 2490521

5

Application of liquid chromatography/thermospray mass spectrometry to studies on the formation of glutathione and cysteine conjugates from monomethylcarbamate metabolites of bambuterol.

Rashed MS, Pearson PG, Han DH, Baillie TA. Rashed MS, et al. Among authors: baillie ta. Rapid Commun Mass Spectrom. 1989 Oct;3(10):360-3. doi: 10.1002/rcm.1290031012. Rapid Commun Mass Spectrom. 1989. PMID: 2520219

6

Applications of tandem mass spectrometry to the characterization of derivatized glutathione conjugates. Studies with S-(N-methylcarbamoyl)glutathione, a metabolite of the antineoplastic agent N-methylformamide.

Pearson PG, Threadgill MD, Howald WN, Baillie TA. Pearson PG, et al. Among authors: baillie ta. Biomed Environ Mass Spectrom. 1988 Oct;16(1-12):51-6. doi: 10.1002/bms.1200160110. Biomed Environ Mass Spectrom. 1988. PMID: 3242707

7

Studies on the metabolic fate of caracemide, an experimental antitumor agent, in the rat. Evidence for the release of methyl isocyanate in vivo.

Slatter JG, Davis MR, Han DH, Pearson PG, Baillie TA. Slatter JG, et al. Among authors: baillie ta. Chem Res Toxicol. 1993 May-Jun;6(3):335-40. doi: 10.1021/tx00033a013. Chem Res Toxicol. 1993. PMID: 8318655

8

In vitro studies on the metabolic activation of the furanopyridine L-754,394, a highly potent and selective mechanism-based inhibitor of cytochrome P450 3A4.

Sahali-Sahly Y, Balani SK, Lin JH, Baillie TA. Sahali-Sahly Y, et al. Among authors: baillie ta. Chem Res Toxicol. 1996 Sep;9(6):1007-12. doi: 10.1021/tx960060b. Chem Res Toxicol. 1996. PMID: 8870989

9

In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.

Prueksaritanont T, Gorham LM, Breslin MJ, Hutchinson JH, Hartman GD, Vyas KP, Baillie TA. Prueksaritanont T, et al. Among authors: baillie ta. Drug Metab Dispos. 1997 Aug;25(8):978-84. Drug Metab Dispos. 1997. PMID: 9280406

10

In vivo assessment of intestinal drug metabolism.

Lin JH, Chiba M, Baillie TA. Lin JH, et al. Among authors: baillie ta. Drug Metab Dispos. 1997 Sep;25(9):1107-9. Drug Metab Dispos. 1997. PMID: 9311630 No abstract available.

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