Chern JH - Search Results

1

Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: a novel class of potent and selective human enterovirus 71 inhibitors.

Shia KS, Li WT, Chang CM, Hsu MC, Chern JH, Leong MK, Tseng SN, Lee CC, Lee YC, Chen SJ, Peng KC, Tseng HY, Chang YL, Tai CL, Shih SR. Shia KS, et al. Among authors: chern jh. J Med Chem. 2002 Apr 11;45(8):1644-55. doi: 10.1021/jm010536a. J Med Chem. 2002. PMID: 11931618

2

Synthesis and in vitro cytotoxicity of 5-substituted 2-cyanoimino-4-imidazodinone and 2-cyanoimino-4-pyrimidinone derivatives.

Chern JH, Shia KS, Chang CM, Lee CC, Lee YC, Tai CL, Lin YT, Chang CS, Tseng HY. Chern JH, et al. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1169-72. doi: 10.1016/j.bmcl.2003.12.073. Bioorg Med Chem Lett. 2004. PMID: 14980658

3

Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidines: a novel class of potent enterovirus inhibitors.

Chern JH, Shia KS, Hsu TA, Tai CL, Lee CC, Lee YC, Chang CS, Tseng SN, Shih SR. Chern JH, et al. Bioorg Med Chem Lett. 2004 May 17;14(10):2519-25. doi: 10.1016/j.bmcl.2004.02.092. Bioorg Med Chem Lett. 2004. PMID: 15109643

4

Mutation in enterovirus 71 capsid protein VP1 confers resistance to the inhibitory effects of pyridyl imidazolidinone.

Shih SR, Tsai MC, Tseng SN, Won KF, Shia KS, Li WT, Chern JH, Chen GW, Lee CC, Lee YC, Peng KC, Chao YS. Shih SR, et al. Among authors: chern jh. Antimicrob Agents Chemother. 2004 Sep;48(9):3523-9. doi: 10.1128/AAC.48.9.3523-3529.2004. Antimicrob Agents Chemother. 2004. PMID: 15328120 Free PMC article.

5

Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones.

Chern JH, Lee CC, Chang CS, Lee YC, Tai CL, Lin YT, Shia KS, Lee CY, Shih SR. Chern JH, et al. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5051-6. doi: 10.1016/j.bmcl.2004.07.084. Bioorg Med Chem Lett. 2004. PMID: 15380197

6

Design, synthesis, and antipicornavirus activity of 1-[5-(4-arylphenoxy)alkyl]-3-pyridin-4-ylimidazolidin-2-one derivatives.

Chang CS, Lin YT, Shih SR, Lee CC, Lee YC, Tai CL, Tseng SN, Chern JH. Chang CS, et al. Among authors: chern jh. J Med Chem. 2005 May 19;48(10):3522-35. doi: 10.1021/jm050033v. J Med Chem. 2005. PMID: 15887961

7

Synthesis and antipicornavirus activity of (R)- and (S)-1-[5-(4'-chlorobiphenyl-4-yloxy)-3-methylpentyl]-3-pyridin-4-yl-imidazolidin-2-one.

Chern JH, Chang CS, Tai CL, Lee YC, Lee CC, Kang IJ, Lee CY, Shih SR. Chern JH, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4206-11. doi: 10.1016/j.bmcl.2005.06.069. Bioorg Med Chem Lett. 2005. PMID: 16054357

8

Design, synthesis, and anti-HCV activity of thiourea compounds.

Kang IJ, Wang LW, Lee CC, Lee YC, Chao YS, Hsu TA, Chern JH. Kang IJ, et al. Among authors: chern jh. Bioorg Med Chem Lett. 2009 Apr 1;19(7):1950-5. doi: 10.1016/j.bmcl.2009.02.048. Epub 2009 Feb 20. Bioorg Med Chem Lett. 2009. PMID: 19251415

9

Design and synthesis of indole, 2,3-dihydro-indole, and 3,4-dihydro-2H-quinoline-1-carbothioic acid amide derivatives as novel HCV inhibitors.

Kang IJ, Wang LW, Hsu SJ, Lee CC, Lee YC, Wu YS, Hsu TA, Yueh A, Chao YS, Chern JH. Kang IJ, et al. Among authors: chern jh. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4134-8. doi: 10.1016/j.bmcl.2009.06.009. Epub 2009 Jun 6. Bioorg Med Chem Lett. 2009. PMID: 19539472

10

Design and efficient synthesis of novel arylthiourea derivatives as potent hepatitis C virus inhibitors.

Kang IJ, Wang LW, Hsu SJ, Lee CC, Lee YC, Wu YS, Yueh A, Wang JC, Hsu TA, Chao YS, Chern JH. Kang IJ, et al. Among authors: chern jh. Bioorg Med Chem Lett. 2009 Nov 1;19(21):6063-8. doi: 10.1016/j.bmcl.2009.09.037. Epub 2009 Sep 17. Bioorg Med Chem Lett. 2009. PMID: 19796940

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