Pyrrolidine dithiocarbamate reduces coxsackievirus B3 replication through inhibition of the ubiquitin-proteasome pathway.
Si X, McManus BM, Zhang J, Yuan J, Cheung C, Esfandiarei M, Suarez A, Morgan A, Luo H.
Si X, et al. Among authors: suarez a.
J Virol. 2005 Jul;79(13):8014-23. doi: 10.1128/JVI.79.13.8014-8023.2005.
J Virol. 2005.
PMID: 15956547
Free PMC article.
In the present study, we report that PDTC is a potent inhibitor of CVB3. Coxsackievirus-infected HeLa cells treated with PDTC showed a significant reduction of CVB3 viral RNA synthesis, viral protein VP1 expression, and viral progeny release. ...Together with our pr …
In the present study, we report that PDTC is a potent inhibitor of CVB3. Coxsackievirus-infected HeLa cells treated with PDTC showed …