Nadler LM - Search Results

1

CD28 costimulation mediates down-regulation of p27kip1 and cell cycle progression by activation of the PI3K/PKB signaling pathway in primary human T cells.

Appleman LJ, van Puijenbroek AA, Shu KM, Nadler LM, Boussiotis VA. Appleman LJ, et al. Among authors: nadler lm. J Immunol. 2002 Mar 15;168(6):2729-36. doi: 10.4049/jimmunol.168.6.2729. J Immunol. 2002. PMID: 11884439

2

cAMP inhibits both Ras and Rap1 activation in primary human T lymphocytes, but only Ras inhibition correlates with blockade of cell cycle progression.

Grader-Beck T, van Puijenbroek AA, Nadler LM, Boussiotis VA. Grader-Beck T, et al. Among authors: nadler lm. Blood. 2003 Feb 1;101(3):998-1006. doi: 10.1182/blood-2002-06-1665. Epub 2002 Sep 19. Blood. 2003. PMID: 12393539 Free article.

3

Differential localization and function of ADP-ribosylation factor-6 in anergic human T cells: a potential marker for their identification.

Tzachanis D, Appleman LJ, Van Puijenbroek AA, Berezovskaya A, Nadler LM, Boussiotis VA. Tzachanis D, et al. Among authors: nadler lm. J Immunol. 2003 Aug 15;171(4):1691-6. doi: 10.4049/jimmunol.171.4.1691. J Immunol. 2003. PMID: 12902467

4

The critical role of CD28 signalling in the prevention of human T-cell anergy.

Boussiotis VA, Freeman GJ, Gribben JG, Nadler LM. Boussiotis VA, et al. Among authors: nadler lm. Res Immunol. 1995 Mar-Apr;146(3):140-9. doi: 10.1016/0923-2494(96)80247-1. Res Immunol. 1995. PMID: 8525043 Review. No abstract available.

5

Induction of T cell clonal anergy results in resistance, whereas CD28-mediated costimulation primes for susceptibility to Fas- and Bax-mediated programmed cell death.

Boussiotis VA, Lee BJ, Freeman GJ, Gribben JG, Nadler LM. Boussiotis VA, et al. Among authors: nadler lm. J Immunol. 1997 Oct 1;159(7):3156-67. J Immunol. 1997. PMID: 9317113

6

The BB1 monoclonal antibody recognizes both cell surface CD74 (MHC class II-associated invariant chain) as well as B7-1 (CD80), resolving the question regarding a third CD28/CTLA-4 counterreceptor.

Freeman GJ, Cardoso AA, Boussiotis VA, Anumanthan A, Groves RW, Kupper TS, Clark EA, Nadler LM. Freeman GJ, et al. Among authors: nadler lm. J Immunol. 1998 Sep 15;161(6):2708-15. J Immunol. 1998. PMID: 9743327

7

Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).

Barata JT, Cardoso AA, Nadler LM, Boussiotis VA. Barata JT, et al. Among authors: nadler lm. Blood. 2001 Sep 1;98(5):1524-31. doi: 10.1182/blood.v98.5.1524. Blood. 2001. PMID: 11520803 Free article.

8

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells.

Tzachanis D, Freeman GJ, Hirano N, van Puijenbroek AA, Delfs MW, Berezovskaya A, Nadler LM, Boussiotis VA. Tzachanis D, et al. Among authors: nadler lm. Nat Immunol. 2001 Dec;2(12):1174-82. doi: 10.1038/ni730. Nat Immunol. 2001. PMID: 11694881

9

Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses.

Tzachanis D, Berezovskaya A, Nadler LM, Boussiotis VA. Tzachanis D, et al. Among authors: nadler lm. Blood. 2002 Feb 15;99(4):1465-73. doi: 10.1182/blood.v99.4.1465. Blood. 2002. PMID: 11830501 Free article.

10

IL-7-dependent human leukemia T-cell line as a valuable tool for drug discovery in T-ALL.

Barata JT, Boussiotis VA, Yunes JA, Ferrando AA, Moreau LA, Veiga JP, Sallan SE, Look AT, Nadler LM, Cardoso AA. Barata JT, et al. Among authors: nadler lm. Blood. 2004 Mar 1;103(5):1891-900. doi: 10.1182/blood-2002-12-3861. Epub 2003 Nov 13. Blood. 2004. PMID: 14615384 Free article.

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