Sachdev P - Search Results

1

Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes.

Sachdev P, Zeng L, Wang LH. Sachdev P, et al. J Biol Chem. 2002 May 17;277(20):17638-48. doi: 10.1074/jbc.M111575200. Epub 2002 Mar 7. J Biol Chem. 2002. PMID: 11884391 Free article.

2

Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.

Zeng L, Sachdev P, Yan L, Chan JL, Trenkle T, McClelland M, Welsh J, Wang LH. Zeng L, et al. Among authors: sachdev p. Mol Cell Biol. 2000 Dec;20(24):9212-24. doi: 10.1128/MCB.20.24.9212-9224.2000. Mol Cell Biol. 2000. PMID: 11094073 Free PMC article.

3

Differential requirement for Rho family GTPases in an oncogenic insulin-like growth factor-I receptor-induced cell transformation.

Sachdev P, Jiang YX, Li W, Miki T, Maruta H, Nur-E-Kamal MS, Wang LH. Sachdev P, et al. J Biol Chem. 2001 Jul 13;276(28):26461-71. doi: 10.1074/jbc.M010995200. Epub 2001 May 9. J Biol Chem. 2001. PMID: 11346642 Free article.

4

The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation.

Nguyen KT, Zong CS, Uttamsingh S, Sachdev P, Bhanot M, Le MT, Chan JL, Wang LH. Nguyen KT, et al. Among authors: sachdev p. J Biol Chem. 2002 Mar 29;277(13):11107-15. doi: 10.1074/jbc.M108166200. Epub 2002 Jan 17. J Biol Chem. 2002. PMID: 11799110 Free article.

5

CXCR7/CXCR4 heterodimer constitutively recruits beta-arrestin to enhance cell migration.

Décaillot FM, Kazmi MA, Lin Y, Ray-Saha S, Sakmar TP, Sachdev P. Décaillot FM, et al. Among authors: sachdev p. J Biol Chem. 2011 Sep 16;286(37):32188-97. doi: 10.1074/jbc.M111.277038. Epub 2011 Jul 5. J Biol Chem. 2011. PMID: 21730065 Free PMC article.

6

Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis.

Ye S, Köhrer C, Huber T, Kazmi M, Sachdev P, Yan ECY, Bhagat A, RajBhandary UL, Sakmar TP. Ye S, et al. Among authors: sachdev p. J Biol Chem. 2008 Jan 18;283(3):1525-1533. doi: 10.1074/jbc.M707355200. Epub 2007 Nov 8. J Biol Chem. 2008. PMID: 17993461 Free article.

7

Mapping the ligand-binding site on a G protein-coupled receptor (GPCR) using genetically encoded photocrosslinkers.

Grunbeck A, Huber T, Sachdev P, Sakmar TP. Grunbeck A, et al. Among authors: sachdev p. Biochemistry. 2011 May 3;50(17):3411-3. doi: 10.1021/bi200214r. Epub 2011 Apr 7. Biochemistry. 2011. PMID: 21417335 Free PMC article.

8

Structural evidence for a sequential release mechanism for activation of heterotrimeric G proteins.

Kapoor N, Menon ST, Chauhan R, Sachdev P, Sakmar TP. Kapoor N, et al. Among authors: sachdev p. J Mol Biol. 2009 Nov 6;393(4):882-97. doi: 10.1016/j.jmb.2009.08.043. Epub 2009 Aug 22. J Mol Biol. 2009. PMID: 19703466

9

Direct interaction between an allosteric agonist pepducin and the chemokine receptor CXCR4.

Janz JM, Ren Y, Looby R, Kazmi MA, Sachdev P, Grunbeck A, Haggis L, Chinnapen D, Lin AY, Seibert C, McMurry T, Carlson KE, Muir TW, Hunt S 3rd, Sakmar TP. Janz JM, et al. Among authors: sachdev p. J Am Chem Soc. 2011 Oct 12;133(40):15878-81. doi: 10.1021/ja206661w. Epub 2011 Sep 21. J Am Chem Soc. 2011. PMID: 21905700

10

G protein beta gamma subunit interaction with the dynein light-chain component Tctex-1 regulates neurite outgrowth.

Sachdev P, Menon S, Kastner DB, Chuang JZ, Yeh TY, Conde C, Caceres A, Sung CH, Sakmar TP. Sachdev P, et al. EMBO J. 2007 Jun 6;26(11):2621-32. doi: 10.1038/sj.emboj.7601716. Epub 2007 May 10. EMBO J. 2007. PMID: 17491591 Free PMC article.

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