Ryder H - Search Results

1

Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multidrug resistance.

Wang S, Ryder H, Pretswell I, Depledge P, Milton J, Hancox TC, Dale I, Dangerfield W, Charlton P, Faint R, Dodd R, Hassan S. Wang S, et al. Among authors: ryder h. Bioorg Med Chem Lett. 2002 Feb 25;12(4):571-4. doi: 10.1016/s0960-894x(01)00804-6. Bioorg Med Chem Lett. 2002. PMID: 11844674

2

Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives.

Roe M, Folkes A, Ashworth P, Brumwell J, Chima L, Hunjan S, Pretswell I, Dangerfield W, Ryder H, Charlton P. Roe M, et al. Among authors: ryder h. Bioorg Med Chem Lett. 1999 Feb 22;9(4):595-600. doi: 10.1016/s0960-894x(99)00030-x. Bioorg Med Chem Lett. 1999. PMID: 10098671

3

Reversal of P-glycoprotein-mediated multidrug resistance by XR9051, a novel diketopiperazine derivative.

Dale IL, Tuffley W, Callaghan R, Holmes JA, Martin K, Luscombe M, Mistry P, Ryder H, Stewart AJ, Charlton P, Twentyman PR, Bevan P. Dale IL, et al. Among authors: ryder h. Br J Cancer. 1998 Oct;78(7):885-92. doi: 10.1038/bjc.1998.597. Br J Cancer. 1998. PMID: 9764579 Free PMC article.

4

In vivo efficacy of XR9051, a potent modulator of P-glycoprotein mediated multidrug resistance.

Mistry P, Plumb J, Eccles S, Watson S, Dale I, Ryder H, Box G, Charlton P, Templeton D, Bevan PB. Mistry P, et al. Among authors: ryder h. Br J Cancer. 1999 Apr;79(11-12):1672-8. doi: 10.1038/sj.bjc.6690267. Br J Cancer. 1999. PMID: 10206276 Free PMC article.

5

New pyrrolopyrimidin-6-yl benzenesulfonamides: potent A2B adenosine receptor antagonists.

Esteve C, Nueda A, Díaz JL, Beleta J, Cárdenas A, Lozoya E, Cadavid MI, Loza MI, Ryder H, Vidal B. Esteve C, et al. Among authors: ryder h. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3642-5. doi: 10.1016/j.bmcl.2006.04.074. Epub 2006 May 11. Bioorg Med Chem Lett. 2006. PMID: 16697192

6

Combinatorial approaches towards the discovery of new tryptase inhibitors.

del Fresno M, Fernández-Forner D, Miralpeix M, Segarra V, Ryder H, Royo M, Albericio F. del Fresno M, et al. Among authors: ryder h. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1659-64. doi: 10.1016/j.bmcl.2005.01.048. Bioorg Med Chem Lett. 2005. PMID: 15745817

7

Synthesis and structure-activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H1 antagonists.

Fonquerna S, Miralpeix M, Pagès L, Puig C, Cardús A, Antón F, Vilella D, Aparici M, Prieto J, Warrellow G, Beleta J, Ryder H. Fonquerna S, et al. Among authors: ryder h. Bioorg Med Chem Lett. 2005 Feb 15;15(4):1165-7. doi: 10.1016/j.bmcl.2004.12.008. Bioorg Med Chem Lett. 2005. PMID: 15686934

8

Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.

Igoe N, Bayle ED, Fedorov O, Tallant C, Savitsky P, Rogers C, Owen DR, Deb G, Somervaille TC, Andrews DM, Jones N, Cheasty A, Ryder H, Brennan PE, Müller S, Knapp S, Fish PV. Igoe N, et al. Among authors: ryder h. J Med Chem. 2017 Jan 26;60(2):668-680. doi: 10.1021/acs.jmedchem.6b01583. Epub 2017 Jan 9. J Med Chem. 2017. PMID: 28068087 Free article.

9

Synthesis and biological activity of pyrido[3',2':4,5]furo[3,2-d]pyrimidine derivatives as novel and potent phosphodiesterase type 4 inhibitors.

Taltavull J, Serrat J, Gràcia J, Gavaldà A, Córdoba M, Calama E, Montero JL, Andrés M, Miralpeix M, Vilella D, Hernández B, Beleta J, Ryder H, Pagès L. Taltavull J, et al. Among authors: ryder h. Eur J Med Chem. 2011 Oct;46(10):4946-56. doi: 10.1016/j.ejmech.2011.07.054. Epub 2011 Aug 5. Eur J Med Chem. 2011. PMID: 21871695

10

Synthesis and biological evaluation of a conformationally free seco-analogue of the immunosuppressant FR901483.

Bonjoch J, Diaba F, Puigbó G, Solé D, Segarra V, Santamaría L, Beleta J, Ryder H, Palacios JM. Bonjoch J, et al. Among authors: ryder h. Bioorg Med Chem. 1999 Dec;7(12):2891-7. doi: 10.1016/s0968-0896(99)00250-3. Bioorg Med Chem. 1999. PMID: 10658593

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