Xie Q - Search Results

1

A novel synthesis of 2-arylpyrrolo[1,2-a]pyrimid-7-ones and their structure-activity relationships as potent GnRH receptor antagonists.

Zhu YF, Wilcoxen K, Saunders J, Guo Z, Gao Y, Connors PJ Jr, Gross TD, Tucci FC, Struthers RS, Reinhart GJ, Xie Q, Chen C. Zhu YF, et al. Among authors: xie q. Bioorg Med Chem Lett. 2002 Feb 11;12(3):403-6. doi: 10.1016/s0960-894x(01)00780-6. Bioorg Med Chem Lett. 2002. PMID: 11814807

2

Design and structure-activity relationships of 2-alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl)imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists.

Zhu YF, Guo Z, Gross TD, Gao Y, Connors PJ Jr, Struthers RS, Xie Q, Tucci FC, Reinhart GJ, Wu D, Saunders J, Chen C. Zhu YF, et al. Among authors: xie q. J Med Chem. 2003 Apr 24;46(9):1769-72. doi: 10.1021/jm0205402. J Med Chem. 2003. PMID: 12699396

3

6,7-dihydroxyisoquinoline-3-carboxylic acids are potent inhibitors on the binding of insulin-like growth factor (IGF) to IGF-binding proteins: optimization of the 1-position benzoyl side chain.

Zhu YF, Wilcoxen K, Gross T, Connors P, Strack N, Gross R, Huang CQ, McCarthy JR, Xie Q, Ling N, Chen C. Zhu YF, et al. Among authors: xie q. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1927-30. doi: 10.1016/s0960-894x(03)00321-4. Bioorg Med Chem Lett. 2003. PMID: 12749900

4

Quinoline-carboxylic acids are potent inhibitors that inhibit the binding of insulin-like growth factor (IGF) to IGF-binding proteins.

Zhu YF, Wang XC, Connors P, Wilcoxen K, Gao Y, Gross R, Strack N, Gross T, McCarthy JR, Xie Q, Ling N, Chen C. Zhu YF, et al. Among authors: xie q. Bioorg Med Chem Lett. 2003 Jun 2;13(11):1931-4. doi: 10.1016/s0960-894x(03)00322-6. Bioorg Med Chem Lett. 2003. PMID: 12749901

5

Synthesis and structure-activity relationships of 1-arylmethyl-3-(2-aminopropyl)-5-aryl-6-methyluracils as potent GnRH receptor antagonists.

Guo Z, Zhu YF, Tucci FC, Gao Y, Struthers RS, Saunders J, Gross TD, Xie Q, Reinhart GJ, Chen C. Guo Z, et al. Among authors: xie q. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3311-5. doi: 10.1016/s0960-894x(03)00620-6. Bioorg Med Chem Lett. 2003. PMID: 12951116

6

Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidine-2,4-dione derivatives as potent GnRH receptor antagonists.

Guo Z, Chen Y, Wu D, Zhu YF, Struthers RS, Saunders J, Xie Q, Chen C. Guo Z, et al. Among authors: xie q. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3617-22. doi: 10.1016/s0960-894x(03)00746-7. Bioorg Med Chem Lett. 2003. PMID: 14505682

7

Synthesis and structure-activity relationships of 1-arylmethyl-5-aryl-6-methyluracils as potent gonadotropin-releasing hormone receptor antagonists.

Guo Z, Zhu YF, Gross TD, Tucci FC, Gao Y, Moorjani M, Connors PJ Jr, Rowbottom MW, Chen Y, Struthers RS, Xie Q, Saunders J, Reinhart G, Chen TK, Bonneville AL, Chen C. Guo Z, et al. Among authors: xie q. J Med Chem. 2004 Feb 26;47(5):1259-71. doi: 10.1021/jm030472z. J Med Chem. 2004. PMID: 14971906

8

Species selectivity of nonpeptide antagonists of the gonadotropin-releasing hormone receptor is determined by residues in extracellular loops II and III and the amino terminus.

Reinhart GJ, Xie Q, Liu XJ, Zhu YF, Fan J, Chen C, Struthers RS. Reinhart GJ, et al. Among authors: xie q. J Biol Chem. 2004 Aug 13;279(33):34115-22. doi: 10.1074/jbc.M404474200. Epub 2004 May 21. J Biol Chem. 2004. PMID: 15155770 Free article.

9

3-(2-aminoalkyl)-1-(2,6-difluorobenzyl)-5- (2-fluoro-3-methoxyphenyl)-6-methyl-uracils as orally bioavailable antagonists of the human gonadotropin releasing hormone receptor.

Tucci FC, Zhu YF, Guo Z, Gross TD, Connors PJ Jr, Gao Y, Rowbottom MW, Struthers RS, Reinhart GJ, Xie Q, Chen TK, Bozigian H, Killam Bonneville AL, Fisher A, Jin L, Saunders J, Chen C. Tucci FC, et al. Among authors: xie q. J Med Chem. 2004 Jul 1;47(14):3483-6. doi: 10.1021/jm049791w. J Med Chem. 2004. PMID: 15214774

10

Synthesis and structure-activity relationships of uracil derived human GnRH receptor antagonists: (R)-3-[2-(2-amino)phenethyl]-1-(2,6-difluorobenzyl)-6-methyluracils containing a substituted thiophene or thiazole at C-5.

Rowbottom MW, Tucci FC, Connors PJ Jr, Gross TD, Zhu YF, Guo Z, Moorjani M, Acevedo O, Carter L, Sullivan SK, Xie Q, Fisher A, Struthers RS, Saunders J, Chen C. Rowbottom MW, et al. Among authors: xie q. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4967-73. doi: 10.1016/j.bmcl.2004.07.022. Bioorg Med Chem Lett. 2004. PMID: 15341961

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

7,113 results

Search Page

Filters