Guo Z - Search Results

1

A novel synthesis of 2-arylpyrrolo[1,2-a]pyrimid-7-ones and their structure-activity relationships as potent GnRH receptor antagonists.

Zhu YF, Wilcoxen K, Saunders J, Guo Z, Gao Y, Connors PJ Jr, Gross TD, Tucci FC, Struthers RS, Reinhart GJ, Xie Q, Chen C. Zhu YF, et al. Among authors: guo z. Bioorg Med Chem Lett. 2002 Feb 11;12(3):403-6. doi: 10.1016/s0960-894x(01)00780-6. Bioorg Med Chem Lett. 2002. PMID: 11814807

2

Design, synthesis and structure-activity relationships of novel imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists.

Gross TD, Zhu YF, Saunders J, Wilcoxen KM, Gao Y, Connors PJ Jr, Guo Z, Struthers RS, Reinhart GJ, Chen C. Gross TD, et al. Among authors: guo z. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2185-7. doi: 10.1016/s0960-894x(02)00371-2. Bioorg Med Chem Lett. 2002. PMID: 12127533

3

A novel synthesis of 7-aryl-8-fluoro-pyrrolo[1,2-a]pyrimid-4-ones as potent, stable GnRH receptor antagonists.

Tucci FC, Zhu YF, Guo Z, Gross TD, Connors PJ Jr, Struthers RS, Reinhart GJ, Wang X, Saunders J, Chen C. Tucci FC, et al. Among authors: guo z. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3491-5. doi: 10.1016/s0960-894x(02)00745-x. Bioorg Med Chem Lett. 2002. PMID: 12419391

4

Design and structure-activity relationships of 2-alkyl-3-aminomethyl-6-(3-methoxyphenyl)-7-methyl-8-(2-fluorobenzyl)imidazolo[1,2-a]pyrimid-5-ones as potent GnRH receptor antagonists.

Zhu YF, Guo Z, Gross TD, Gao Y, Connors PJ Jr, Struthers RS, Xie Q, Tucci FC, Reinhart GJ, Wu D, Saunders J, Chen C. Zhu YF, et al. Among authors: guo z. J Med Chem. 2003 Apr 24;46(9):1769-72. doi: 10.1021/jm0205402. J Med Chem. 2003. PMID: 12699396

5

Identification of 1-arylmethyl-3- (2-aminoethyl)-5-aryluracil as novel gonadotropin-releasing hormone receptor antagonists.

Zhu YF, Gross TD, Guo Z, Connors PJ Jr, Gao Y, Tucci FC, Struthers RS, Reinhart GJ, Saunders J, Chen TK, Killam Bonneville AL, Chen C. Zhu YF, et al. Among authors: guo z. J Med Chem. 2003 May 22;46(11):2023-6. doi: 10.1021/jm034041s. J Med Chem. 2003. PMID: 12747774

6

Synthesis and structure-activity relationships of 1-arylmethyl-3-(2-aminopropyl)-5-aryl-6-methyluracils as potent GnRH receptor antagonists.

Guo Z, Zhu YF, Tucci FC, Gao Y, Struthers RS, Saunders J, Gross TD, Xie Q, Reinhart GJ, Chen C. Guo Z, et al. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3311-5. doi: 10.1016/s0960-894x(03)00620-6. Bioorg Med Chem Lett. 2003. PMID: 12951116

7

Synthesis and structure-activity relationships of 1-arylmethyl-3-(1-methyl-2-amino)ethyl-5-aryl-6-methyluracils as antagonists of the human GnRH Receptor.

Tucci FC, Zhu YF, Guo Z, Gross TD, Connors PJ Jr, Struthers RS, Reinhart GJ, Saunders J, Chen C. Tucci FC, et al. Among authors: guo z. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3317-22. doi: 10.1016/s0960-894x(03)00619-x. Bioorg Med Chem Lett. 2003. PMID: 12951117

8

Synthesis and structure-activity relationships of thieno[2,3-d]pyrimidine-2,4-dione derivatives as potent GnRH receptor antagonists.

Guo Z, Chen Y, Wu D, Zhu YF, Struthers RS, Saunders J, Xie Q, Chen C. Guo Z, et al. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3617-22. doi: 10.1016/s0960-894x(03)00746-7. Bioorg Med Chem Lett. 2003. PMID: 14505682

9

Synthesis and structure-activity relationships of 1-arylmethyl-5-aryl-6-methyluracils as potent gonadotropin-releasing hormone receptor antagonists.

Guo Z, Zhu YF, Gross TD, Tucci FC, Gao Y, Moorjani M, Connors PJ Jr, Rowbottom MW, Chen Y, Struthers RS, Xie Q, Saunders J, Reinhart G, Chen TK, Bonneville AL, Chen C. Guo Z, et al. J Med Chem. 2004 Feb 26;47(5):1259-71. doi: 10.1021/jm030472z. J Med Chem. 2004. PMID: 14971906

10

Synthesis and structure-activity relationships of (R)-1-alkyl-3-[2-(2-amino)phenethyl]-5-(2-fluorophenyl)-6-methyluracils as human GnRH receptor antagonists.

Rowbottom MW, Tucci FC, Zhu YF, Guo Z, Gross TD, Reinhart GJ, Xie Q, Struthers RS, Saunders J, Chen C. Rowbottom MW, et al. Among authors: guo z. Bioorg Med Chem Lett. 2004 May 3;14(9):2269-74. doi: 10.1016/j.bmcl.2004.02.004. Bioorg Med Chem Lett. 2004. PMID: 15081023

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