Kliewer SA - Search Results

1

Regulation of cyp3a gene transcription by the pregnane x receptor.

Goodwin B, Redinbo MR, Kliewer SA. Goodwin B, et al. Among authors: kliewer sa. Annu Rev Pharmacol Toxicol. 2002;42:1-23. doi: 10.1146/annurev.pharmtox.42.111901.111051. Annu Rev Pharmacol Toxicol. 2002. PMID: 11807162 Review.

2

Nuclear receptors. I. Nuclear receptors and bile acid homeostasis.

Goodwin B, Kliewer SA. Goodwin B, et al. Among authors: kliewer sa. Am J Physiol Gastrointest Liver Physiol. 2002 Jun;282(6):G926-31. doi: 10.1152/ajpgi.00044.2002. Am J Physiol Gastrointest Liver Physiol. 2002. PMID: 12016116 Free article. Review.

3

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Maglich JM, et al. Among authors: kliewer sa. Mol Pharmacol. 2002 Sep;62(3):638-46. doi: 10.1124/mol.62.3.638. Mol Pharmacol. 2002. PMID: 12181440

4

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

Kliewer SA, Goodwin B, Willson TM. Kliewer SA, et al. Endocr Rev. 2002 Oct;23(5):687-702. doi: 10.1210/er.2001-0038. Endocr Rev. 2002. PMID: 12372848 Review.

5

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Among authors: kliewer sa. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

6

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor.

Goodwin B, Gauthier KC, Umetani M, Watson MA, Lochansky MI, Collins JL, Leitersdorf E, Mangelsdorf DJ, Kliewer SA, Repa JJ. Goodwin B, et al. Among authors: kliewer sa. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):223-8. doi: 10.1073/pnas.0237082100. Epub 2002 Dec 30. Proc Natl Acad Sci U S A. 2003. PMID: 12509506 Free PMC article.

7

Structural basis of human pregnane X receptor activation by the hops constituent colupulone.

Teotico DG, Bischof JJ, Peng L, Kliewer SA, Redinbo MR. Teotico DG, et al. Among authors: kliewer sa. Mol Pharmacol. 2008 Dec;74(6):1512-20. doi: 10.1124/mol.108.050732. Epub 2008 Sep 2. Mol Pharmacol. 2008. PMID: 18768384 Free PMC article.

8

Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.

Moore LB, Parks DJ, Jones SA, Bledsoe RK, Consler TG, Stimmel JB, Goodwin B, Liddle C, Blanchard SG, Willson TM, Collins JL, Kliewer SA. Moore LB, et al. Among authors: kliewer sa. J Biol Chem. 2000 May 19;275(20):15122-7. doi: 10.1074/jbc.M001215200. J Biol Chem. 2000. PMID: 10748001 Free article.

9

St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor.

Moore LB, Goodwin B, Jones SA, Wisely GB, Serabjit-Singh CJ, Willson TM, Collins JL, Kliewer SA. Moore LB, et al. Among authors: kliewer sa. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7500-2. doi: 10.1073/pnas.130155097. Proc Natl Acad Sci U S A. 2000. PMID: 10852961 Free PMC article.

10

Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.

Goodwin B, Moore LB, Stoltz CM, McKee DD, Kliewer SA. Goodwin B, et al. Among authors: kliewer sa. Mol Pharmacol. 2001 Sep;60(3):427-31. Mol Pharmacol. 2001. PMID: 11502872

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