Salvadori S - Search Results

1

Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties.

Balboni G, Guerrini R, Salvadori S, Bianchi C, Rizzi D, Bryant SD, Lazarus LH. Balboni G, et al. Among authors: salvadori s. J Med Chem. 2002 Jan 31;45(3):713-20. doi: 10.1021/jm010449i. J Med Chem. 2002. PMID: 11806723

2

Crystal structures of dipeptides containing the Dmt-Tic pharmacophore.

Bryant SD, George C, Flippen-Anderson JL, Deschamps JR, Salvadori S, Balboni G, Guerrini R, Lazarus LH. Bryant SD, et al. Among authors: salvadori s. J Med Chem. 2002 Dec 5;45(25):5506-13. doi: 10.1021/jm020330p. J Med Chem. 2002. PMID: 12459018

3

Potent delta-opioid receptor agonists containing the Dmt-Tic pharmacophore.

Balboni G, Salvadori S, Guerrini R, Negri L, Giannini E, Jinsmaa Y, Bryant SD, Lazarus LH. Balboni G, et al. Among authors: salvadori s. J Med Chem. 2002 Dec 5;45(25):5556-63. doi: 10.1021/jm020336e. J Med Chem. 2002. PMID: 12459023

4

Unique high-affinity synthetic mu-opioid receptor agonists with central- and systemic-mediated analgesia.

Okada Y, Tsuda Y, Fujita Y, Yokoi T, Sasaki Y, Ambo A, Konishi R, Nagata M, Salvadori S, Jinsmaa Y, Bryant SD, Lazarus LH. Okada Y, et al. Among authors: salvadori s. J Med Chem. 2003 Jul 17;46(15):3201-9. doi: 10.1021/jm020459z. J Med Chem. 2003. PMID: 12852751

5

Synthesis and opioid activity of N,N-dimethyl-Dmt-Tic-NH-CH(R)-R' analogues: acquisition of potent delta antagonism.

Balboni G, Salvadori S, Guerrini R, Negri L, Giannini E, Bryant SD, Jinsmaa Y, Lazarus LH. Balboni G, et al. Among authors: salvadori s. Bioorg Med Chem. 2003 Dec 1;11(24):5435-41. doi: 10.1016/j.bmc.2003.09.039. Bioorg Med Chem. 2003. PMID: 14642588

6

Direct influence of C-terminally substituted amino acids in the Dmt-Tic pharmacophore on delta-opioid receptor selectivity and antagonism.

Balboni G, Salvadori S, Guerrini R, Negri L, Giannini E, Bryant SD, Jinsmaa Y, Lazarus LH. Balboni G, et al. Among authors: salvadori s. J Med Chem. 2004 Jul 29;47(16):4066-71. doi: 10.1021/jm040033f. J Med Chem. 2004. PMID: 15267245

7

Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.

Balboni G, Salvadori S, Dal Piaz A, Bortolotti F, Argazzi R, Negri L, Lattanzi R, Bryant SD, Jinsmaa Y, Lazarus LH. Balboni G, et al. Among authors: salvadori s. J Med Chem. 2004 Dec 16;47(26):6541-6. doi: 10.1021/jm040128h. J Med Chem. 2004. PMID: 15588089

8

N- and C-terminal modifications of nociceptin/orphanin FQ generate highly potent NOP receptor ligands.

Guerrini R, Caló G, Lambert DG, Carrá G, Arduin M, Barnes TA, McDonald J, Rizzi D, Trapella C, Marzola E, Rowbotham DJ, Regoli D, Salvadori S. Guerrini R, et al. Among authors: salvadori s. J Med Chem. 2005 Mar 10;48(5):1421-7. doi: 10.1021/jm040106v. J Med Chem. 2005. PMID: 15743186

9

From the potent and selective mu opioid receptor agonist H-Dmt-d-Arg-Phe-Lys-NH(2) to the potent delta antagonist H-Dmt-Tic-Phe-Lys(Z)-OH.

Balboni G, Cocco MT, Salvadori S, Romagnoli R, Sasaki Y, Okada Y, Bryant SD, Jinsmaa Y, Lazarus LH. Balboni G, et al. Among authors: salvadori s. J Med Chem. 2005 Aug 25;48(17):5608-11. doi: 10.1021/jm0504959. J Med Chem. 2005. PMID: 16107162

10

Potent Dmt-Tic pharmacophoric delta- and mu-opioid receptor antagonists.

Li T, Fujita Y, Shiotani K, Miyazaki A, Tsuda Y, Ambo A, Sasaki Y, Jinsmaa Y, Marczak E, Bryant SD, Salvadori S, Lazarus LH, Okada Y. Li T, et al. Among authors: salvadori s. J Med Chem. 2005 Dec 15;48(25):8035-44. doi: 10.1021/jm050377l. J Med Chem. 2005. PMID: 16335927

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