Maier MA - Search Results

1

Nuclease resistance of oligonucleotides containing the tricyclic cytosine analogues phenoxazine and 9-(2-aminoethoxy)-phenoxazine ("G-clamp") and origins of their nuclease resistance properties.

Maier MA, Leeds JM, Balow G, Springer RH, Bharadwaj R, Manoharan M. Maier MA, et al. Biochemistry. 2002 Jan 29;41(4):1323-7. doi: 10.1021/bi011725y. Biochemistry. 2002. PMID: 11802733

2

Synthesis of chimeric oligonucleotides containing phosphodiester, phosphorothioate, and phosphoramidate linkages.

Maier MA, Guzaev AP, Manoharan M. Maier MA, et al. Org Lett. 2000 Jun 29;2(13):1819-22. doi: 10.1021/ol005842h. Org Lett. 2000. PMID: 10891166

3

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

An H, Wang T, Maier MA, Manoharan M, Ross BS, Cook PD. An H, et al. Among authors: maier ma. J Org Chem. 2001 Apr 20;66(8):2789-801. doi: 10.1021/jo001699u. J Org Chem. 2001. PMID: 11304203

4

Peptide nucleic acids are potent modulators of endogenous pre-mRNA splicing of the murine interleukin-5 receptor-alpha chain.

Karras JG, Maier MA, Lu T, Watt A, Manoharan M. Karras JG, et al. Among authors: maier ma. Biochemistry. 2001 Jul 3;40(26):7853-9. doi: 10.1021/bi010263l. Biochemistry. 2001. PMID: 11425312

5

Inhibition of (cytosine C5)-methyltransferase by oligonucleotides containing flexible (cyclopentane) and conformationally constrained (bicyclo[3.1.0]hexane) abasic sites.

Marquez VE, Wang P, Nicklaus MC, Maier M, Manoharan M, Christman JK, Banavali NK, Mackerell AD Jr. Marquez VE, et al. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):451-9. doi: 10.1081/NCN-100002319. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563060 Review.

6

Systemically delivered antisense oligomers upregulate gene expression in mouse tissues.

Sazani P, Gemignani F, Kang SH, Maier MA, Manoharan M, Persmark M, Bortner D, Kole R. Sazani P, et al. Among authors: maier ma. Nat Biotechnol. 2002 Dec;20(12):1228-33. doi: 10.1038/nbt759. Epub 2002 Nov 11. Nat Biotechnol. 2002. PMID: 12426578

7

High-affinity peptide nucleic acid oligomers containing tricyclic cytosine analogues.

Rajeev KG, Maier MA, Lesnik EA, Manoharan M. Rajeev KG, et al. Among authors: maier ma. Org Lett. 2002 Dec 12;4(25):4395-8. doi: 10.1021/ol027026a. Org Lett. 2002. PMID: 12465896

8

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Wilds CJ, et al. Among authors: maier ma. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):115-7. doi: 10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491456 No abstract available.

9

Synthesis of antisense oligonucleotides conjugated to a multivalent carbohydrate cluster for cellular targeting.

Maier MA, Yannopoulos CG, Mohamed N, Roland A, Fritz H, Mohan V, Just G, Manoharan M. Maier MA, et al. Bioconjug Chem. 2003 Jan-Feb;14(1):18-29. doi: 10.1021/bc020028v. Bioconjug Chem. 2003. PMID: 12526688

10

Synthesis and characterization of oligonucleotides containing conformationally constrained bicyclo[3.1.0]hexane pseudosugar analogs.

Maier MA, Choi Y, Gaus H, Barchi JJ Jr, Marquez VE, Manoharan M. Maier MA, et al. Nucleic Acids Res. 2004 Jul 9;32(12):3642-50. doi: 10.1093/nar/gkh667. Print 2004. Nucleic Acids Res. 2004. PMID: 15247346 Free PMC article.

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