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Insights in vessel development and vascular disorders using targeted inactivation and transfer of vascular endothelial growth factor, the tissue factor receptor, and the plasminogen system.
Carmeliet P, Moons L, Dewerchin M, Mackman N, Luther T, Breier G, Ploplis V, Müller M, Nagy A, Plow E, Gerard R, Edgington T, Risau W, Collen D. Carmeliet P, et al. Ann N Y Acad Sci. 1997 Apr 15;811:191-206. doi: 10.1111/j.1749-6632.1997.tb52002.x. Ann N Y Acad Sci. 1997. PMID: 9186598 Review.
Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure.
Heymans S, Luttun A, Nuyens D, Theilmeier G, Creemers E, Moons L, Dyspersin GD, Cleutjens JP, Shipley M, Angellilo A, Levi M, Nübe O, Baker A, Keshet E, Lupu F, Herbert JM, Smits JF, Shapiro SD, Baes M, Borgers M, Collen D, Daemen MJ, Carmeliet P. Heymans S, et al. Among authors: carmeliet p. Nat Med. 1999 Oct;5(10):1135-42. doi: 10.1038/13459. Nat Med. 1999. PMID: 10502816
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.
Carmeliet P, Moons L, Luttun A, Vincenti V, Compernolle V, De Mol M, Wu Y, Bono F, Devy L, Beck H, Scholz D, Acker T, DiPalma T, Dewerchin M, Noel A, Stalmans I, Barra A, Blacher S, VandenDriessche T, Ponten A, Eriksson U, Plate KH, Foidart JM, Schaper W, Charnock-Jones DS, Hicklin DJ, Herbert JM, Collen D, Persico MG. Carmeliet P, et al. Nat Med. 2001 May;7(5):575-83. doi: 10.1038/87904. Nat Med. 2001. PMID: 11329059 Free article.
784 results