Maeshima Y - Search Results

1

Tumstatin, an endothelial cell-specific inhibitor of protein synthesis.

Maeshima Y, Sudhakar A, Lively JC, Ueki K, Kharbanda S, Kahn CR, Sonenberg N, Hynes RO, Kalluri R. Maeshima Y, et al. Science. 2002 Jan 4;295(5552):140-3. doi: 10.1126/science.1065298. Science. 2002. PMID: 11778052

2

Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin.

Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R. Hamano Y, et al. Among authors: maeshima y. Cancer Cell. 2003 Jun;3(6):589-601. doi: 10.1016/s1535-6108(03)00133-8. Cancer Cell. 2003. PMID: 12842087 Free PMC article.

3

Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties.

Maeshima Y, Colorado PC, Kalluri R. Maeshima Y, et al. J Biol Chem. 2000 Aug 4;275(31):23745-50. doi: 10.1074/jbc.C000186200. J Biol Chem. 2000. PMID: 10837460 Free article.

Tumstatin (alpha3(IV)NC1 domain) is one such novel molecule with distinct anti-tumor properties and possesses an N-terminal (amino acids 54-132) anti-angiogenic and a C-terminal (amino acids 185-203) anti-tumor cell activity (Maeshima, Y., et al. 2000) J. Biol. Chem …

Tumstatin (alpha3(IV)NC1 domain) is one such novel molecule with distinct anti-tumor properties and possesses an N-terminal (amino acids 54- …

4

Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin.

Maeshima Y, Manfredi M, Reimer C, Holthaus KA, Hopfer H, Chandamuri BR, Kharbanda S, Kalluri R. Maeshima Y, et al. J Biol Chem. 2001 May 4;276(18):15240-8. doi: 10.1074/jbc.M007764200. Epub 2001 Feb 7. J Biol Chem. 2001. PMID: 11278365 Free article.

5

Bifunctional promoter of type IV collagen COL4A5 and COL4A6 genes regulates the expression of alpha5 and alpha6 chains in a distinct cell-specific fashion.

Sund M, Maeshima Y, Kalluri R. Sund M, et al. Among authors: maeshima y. Biochem J. 2005 May 1;387(Pt 3):755-61. doi: 10.1042/BJ20041870. Biochem J. 2005. PMID: 15598179 Free PMC article.

6

Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity.

Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R. Eikesdal HP, et al. Among authors: maeshima y. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15040-5. doi: 10.1073/pnas.0807055105. Epub 2008 Sep 25. Proc Natl Acad Sci U S A. 2008. PMID: 18818312 Free PMC article.

7

Extracellular matrix-derived peptide binds to alpha(v)beta(3) integrin and inhibits angiogenesis.

Maeshima Y, Yerramalla UL, Dhanabal M, Holthaus KA, Barbashov S, Kharbanda S, Reimer C, Manfredi M, Dickerson WM, Kalluri R. Maeshima Y, et al. J Biol Chem. 2001 Aug 24;276(34):31959-68. doi: 10.1074/jbc.M103024200. Epub 2001 Jun 8. J Biol Chem. 2001. PMID: 11399763 Free article.

8

Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth.

Kamphaus GD, Colorado PC, Panka DJ, Hopfer H, Ramchandran R, Torre A, Maeshima Y, Mier JW, Sukhatme VP, Kalluri R. Kamphaus GD, et al. Among authors: maeshima y. J Biol Chem. 2000 Jan 14;275(2):1209-15. doi: 10.1074/jbc.275.2.1209. J Biol Chem. 2000. PMID: 10625665 Free article.

9

Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models.

Zeisberg M, Bottiglio C, Kumar N, Maeshima Y, Strutz F, Müller GA, Kalluri R. Zeisberg M, et al. Among authors: maeshima y. Am J Physiol Renal Physiol. 2003 Dec;285(6):F1060-7. doi: 10.1152/ajprenal.00191.2002. Epub 2003 Aug 12. Am J Physiol Renal Physiol. 2003. PMID: 12915382 Free article.

10

Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells.

Zeisberg M, Maeshima Y, Mosterman B, Kalluri R. Zeisberg M, et al. Among authors: maeshima y. Am J Pathol. 2002 Jun;160(6):2001-8. doi: 10.1016/S0002-9440(10)61150-9. Am J Pathol. 2002. PMID: 12057905 Free PMC article.

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