Poli S - Search Results

1

Use of isotopes and LC-MS-ESI-TOF for mechanistic studies of tienilic acid metabolic activation.

Belghazi M, Jean P, Poli S, Schmitter JM, Mansuy D, Dansette PM. Belghazi M, et al. Among authors: poli s. Adv Exp Med Biol. 2001;500:139-44. doi: 10.1007/978-1-4615-0667-6_17. Adv Exp Med Biol. 2001. PMID: 11764926 No abstract available.

2

Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9.

Mancy A, Dijols S, Poli S, Guengerich P, Mansuy D. Mancy A, et al. Among authors: poli s. Biochemistry. 1996 Dec 17;35(50):16205-12. doi: 10.1021/bi961950t. Biochemistry. 1996. PMID: 8973193

3

Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.

Fontana E, Dansette PM, Poli SM. Fontana E, et al. Among authors: poli sm. Curr Drug Metab. 2005 Oct;6(5):413-54. doi: 10.2174/138920005774330639. Curr Drug Metab. 2005. PMID: 16248836 Review.

4

Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists.

Hoffmann T, Bös M, Stadler H, Schnider P, Hunkeler W, Godel T, Galley G, Ballard TM, Higgins GA, Poli SM, Sleight AJ. Hoffmann T, et al. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1362-5. doi: 10.1016/j.bmcl.2005.11.047. Epub 2005 Dec 5. Bioorg Med Chem Lett. 2006. PMID: 16332435

5

The chloroperoxidase-catalyzed oxidation of phenols. Mechanism, selectivity, and characterization of enzyme-substrate complexes.

Casella L, Poli S, Gullotti M, Selvaggini C, Beringhelli T, Marchesini A. Casella L, et al. Among authors: poli s. Biochemistry. 1994 May 31;33(21):6377-86. doi: 10.1021/bi00187a001. Biochemistry. 1994. PMID: 8204570

6

An aminomethylpyrimidine DPP-IV inhibitor with improved properties.

Peters JU, Hunziker D, Fischer H, Kansy M, Weber S, Kritter S, Müller A, Wallier A, Ricklin F, Boehringer M, Poli SM, Csato M, Loeffler BM. Peters JU, et al. Among authors: poli sm. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3575-8. doi: 10.1016/j.bmcl.2004.04.048. Bioorg Med Chem Lett. 2004. PMID: 15177477

7

Mechanism of enantioselective oxygenation of sulfides catalyzed by chloroperoxidase and horseradish peroxidase. Spectral studies and characterization of enzyme-substrate complexes.

Casella L, Gullotti M, Ghezzi R, Poli S, Beringhelli T, Colonna S, Carrea G. Casella L, et al. Among authors: poli s. Biochemistry. 1992 Oct 6;31(39):9451-9. doi: 10.1021/bi00154a018. Biochemistry. 1992. PMID: 1390727

8

Novel hexahydrospiro[piperidine-4,1'-pyrrolo[3,4-c]pyrroles]: highly selective small-molecule nociceptin/orphanin FQ receptor agonists.

Kolczewski S, Adam G, Cesura AM, Jenck F, Hennig M, Oberhauser T, Poli SM, Rössler F, Röver S, Wichmann J, Dautzenberg FM. Kolczewski S, et al. Among authors: poli sm. J Med Chem. 2003 Jan 16;46(2):255-64. doi: 10.1021/jm0209174. J Med Chem. 2003. PMID: 12519064

9

Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.

Schwab D, Fischer H, Tabatabaei A, Poli S, Huwyler J. Schwab D, et al. Among authors: poli s. J Med Chem. 2003 Apr 24;46(9):1716-25. doi: 10.1021/jm021012t. J Med Chem. 2003. PMID: 12699389

10

Discovery of potent, balanced and orally active dual NK1/NK3 receptor ligands.

Peters JU, Hoffmann T, Schnider P, Stadler H, Koblet A, Alker A, Poli SM, Ballard TM, Spooren W, Steward L, Sleight AJ. Peters JU, et al. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3405-8. doi: 10.1016/j.bmcl.2010.04.008. Epub 2010 Apr 9. Bioorg Med Chem Lett. 2010. PMID: 20430616

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