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Phenoxyphenyl sulfone N-formylhydroxylamines (retrohydroxamates) as potent, selective, orally bioavailable matrix metalloproteinase inhibitors.
J Med Chem. 2002 Jan 3;45(1):219-32. doi: 10.1021/jm0103920.
J Med Chem. 2002.
PMID: 11754593
Evaluation of the inhibition of other metalloproteinases by matrix metalloproteinase inhibitors.
Marcotte PA, Elmore IN, Guan Z, Magoc TJ, Albert DH, Morgand DW, Curtin ML, Garland RB, Guo Y, Heyman HR, Holms JH, Sheppard GS, Steinman DH, Wada CK, Davidsen SK.
Marcotte PA, et al. Among authors: elmore in.
J Enzyme Inhib. 1999;14(6):425-35. doi: 10.3109/14756369909030333.
J Enzyme Inhib. 1999.
PMID: 10536876
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Aryl ketones as novel replacements for the C-terminal amide bond of succinyl hydroxamate MMP inhibitors.
Sheppard GS, Florjancic AS, Giesler JR, Xu L, Guo Y, Davidsen SK, Marcotte PA, Elmore I, Albert DH, Magoc TJ, Bouska JJ, Goodfellow CL, Morgan DW, Summers JB.
Sheppard GS, et al.
Bioorg Med Chem Lett. 1998 Nov 17;8(22):3251-6. doi: 10.1016/s0960-894x(98)00597-6.
Bioorg Med Chem Lett. 1998.
PMID: 9873712
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Discovery of selective hydroxamic acid inhibitors of tumor necrosis factor-alpha converting enzyme.
Holms J, Mast K, Marcotte P, Elmore I, Li J, Pease L, Glaser K, Morgan D, Michaelides M, Davidsen S.
Holms J, et al.
Bioorg Med Chem Lett. 2001 Nov 19;11(22):2907-10. doi: 10.1016/s0960-894x(01)00603-5.
Bioorg Med Chem Lett. 2001.
PMID: 11677124
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