Huber R - Search Results

1

Structural basis for the activation of human procaspase-7.

Riedl SJ, Fuentes-Prior P, Renatus M, Kairies N, Krapp S, Huber R, Salvesen GS, Bode W. Riedl SJ, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14790-5. doi: 10.1073/pnas.221580098. Proc Natl Acad Sci U S A. 2001. PMID: 11752425 Free PMC article.

2

X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B.

Brandstetter H, Bauer M, Huber R, Lollar P, Bode W. Brandstetter H, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 1995 Oct 10;92(21):9796-800. doi: 10.1073/pnas.92.21.9796. Proc Natl Acad Sci U S A. 1995. PMID: 7568220 Free PMC article.

3

Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug.

Fuentes-Prior P, Noeske-Jungblut C, Donner P, Schleuning WD, Huber R, Bode W. Fuentes-Prior P, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11845-50. doi: 10.1073/pnas.94.22.11845. Proc Natl Acad Sci U S A. 1997. PMID: 9342325 Free PMC article.

4

New enzyme lineages by subdomain shuffling.

Hopfner KP, Kopetzki E, Kresse GB, Bode W, Huber R, Engh RA. Hopfner KP, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):9813-8. doi: 10.1073/pnas.95.17.9813. Proc Natl Acad Sci U S A. 1998. PMID: 9707558 Free PMC article.

5

The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium.

Strobl S, Fernandez-Catalan C, Braun M, Huber R, Masumoto H, Nakagawa K, Irie A, Sorimachi H, Bourenkow G, Bartunik H, Suzuki K, Bode W. Strobl S, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):588-92. doi: 10.1073/pnas.97.2.588. Proc Natl Acad Sci U S A. 2000. PMID: 10639123 Free PMC article.

6

Structural basis of the endoproteinase-protein inhibitor interaction.

Bode W, Huber R. Bode W, et al. Among authors: huber r. Biochim Biophys Acta. 2000 Mar 7;1477(1-2):241-52. doi: 10.1016/s0167-4838(99)00276-9. Biochim Biophys Acta. 2000. PMID: 10708861 Review.

7

The 2.0-A crystal structure of tachylectin 5A provides evidence for the common origin of the innate immunity and the blood coagulation systems.

Kairies N, Beisel HG, Fuentes-Prior P, Tsuda R, Muta T, Iwanaga S, Bode W, Huber R, Kawabata S. Kairies N, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13519-24. doi: 10.1073/pnas.201523798. Epub 2001 Nov 13. Proc Natl Acad Sci U S A. 2001. PMID: 11707569 Free PMC article.

8

The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism.

Engel M, Hoffmann T, Wagner L, Wermann M, Heiser U, Kiefersauer R, Huber R, Bode W, Demuth HU, Brandstetter H. Engel M, et al. Among authors: huber r. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5063-8. doi: 10.1073/pnas.0230620100. Epub 2003 Apr 10. Proc Natl Acad Sci U S A. 2003. PMID: 12690074 Free PMC article.

9

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation.

Friedrich R, Panizzi P, Fuentes-Prior P, Richter K, Verhamme I, Anderson PJ, Kawabata S, Huber R, Bode W, Bock PE. Friedrich R, et al. Among authors: huber r. Nature. 2003 Oct 2;425(6957):535-9. doi: 10.1038/nature01962. Nature. 2003. PMID: 14523451

10

Structural basis of the zinc inhibition of human tissue kallikrein 5.

Debela M, Goettig P, Magdolen V, Huber R, Schechter NM, Bode W. Debela M, et al. Among authors: huber r. J Mol Biol. 2007 Nov 2;373(4):1017-31. doi: 10.1016/j.jmb.2007.08.042. Epub 2007 Aug 24. J Mol Biol. 2007. PMID: 17881000

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