Williams JI - Search Results

1

A phase I and pharmacokinetic study of squalamine, a novel antiangiogenic agent, in patients with advanced cancers.

Bhargava P, Marshall JL, Dahut W, Rizvi N, Trocky N, Williams JI, Hait H, Song S, Holroyd KJ, Hawkins MJ. Bhargava P, et al. Among authors: williams ji. Clin Cancer Res. 2001 Dec;7(12):3912-9. Clin Cancer Res. 2001. PMID: 11751482 Clinical Trial.

2

A Phase I and pharmacokinetic study of squalamine, an aminosterol angiogenesis inhibitor.

Hao D, Hammond LA, Eckhardt SG, Patnaik A, Takimoto CH, Schwartz GH, Goetz AD, Tolcher AW, McCreery HA, Mamun K, Williams JI, Holroyd KJ, Rowinsky EK. Hao D, et al. Among authors: williams ji. Clin Cancer Res. 2003 Jul;9(7):2465-71. Clin Cancer Res. 2003. PMID: 12855619 Clinical Trial.

3

A phase I/IIA trial of continuous five-day infusion of squalamine lactate (MSI-1256F) plus carboplatin and paclitaxel in patients with advanced non-small cell lung cancer.

Herbst RS, Hammond LA, Carbone DP, Tran HT, Holroyd KJ, Desai A, Williams JI, Bekele BN, Hait H, Allgood V, Solomon S, Schiller JH. Herbst RS, et al. Among authors: williams ji. Clin Cancer Res. 2003 Sep 15;9(11):4108-15. Clin Cancer Res. 2003. PMID: 14519633 Clinical Trial.

4

Squalamine treatment of human tumors in nu/nu mice enhances platinum-based chemotherapies.

Williams JI, Weitman S, Gonzalez CM, Jundt CH, Marty J, Stringer SD, Holroyd KJ, Mclane MP, Chen Q, Zasloff M, Von Hoff DD. Williams JI, et al. Clin Cancer Res. 2001 Mar;7(3):724-33. Clin Cancer Res. 2001. PMID: 11297269

5

Squalamine lactate reduces choroidal neovascularization in a laser-injury model in the rat.

Ciulla TA, Criswell MH, Danis RP, Williams JI, McLane MP, Holroyd KJ. Ciulla TA, et al. Among authors: williams ji. Retina. 2003 Dec;23(6):808-14. doi: 10.1097/00006982-200312000-00011. Retina. 2003. PMID: 14707832

6

Effect of squalamine on iris neovascularization in monkeys.

Genaidy M, Kazi AA, Peyman GA, Passos-Machado E, Farahat HG, Williams JI, Holroyd KJ, Blake DA. Genaidy M, et al. Among authors: williams ji. Retina. 2002 Dec;22(6):772-8. doi: 10.1097/00006982-200212000-00014. Retina. 2002. PMID: 12476105

7

Regression of retinopathy by squalamine in a mouse model.

Higgins RD, Yan Y, Geng Y, Zasloff M, Williams JI. Higgins RD, et al. Among authors: williams ji. Pediatr Res. 2004 Jul;56(1):144-9. doi: 10.1203/01.PDR.0000128977.55799.34. Epub 2004 May 5. Pediatr Res. 2004. PMID: 15128931

8

Squalamine improves retinal neovascularization.

Higgins RD, Sanders RJ, Yan Y, Zasloff M, Williams JI. Higgins RD, et al. Among authors: williams ji. Invest Ophthalmol Vis Sci. 2000 May;41(6):1507-12. Invest Ophthalmol Vis Sci. 2000. PMID: 10798670

9

A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties.

Zasloff M, Williams JI, Chen Q, Anderson M, Maeder T, Holroyd K, Jones S, Kinney W, Cheshire K, McLane M. Zasloff M, et al. Among authors: williams ji. Int J Obes Relat Metab Disord. 2001 May;25(5):689-97. doi: 10.1038/sj.ijo.0801599. Int J Obes Relat Metab Disord. 2001. PMID: 11360152

10

Squalamine and cisplatin block angiogenesis and growth of human ovarian cancer cells with or without HER-2 gene overexpression.

Li D, Williams JI, Pietras RJ. Li D, et al. Among authors: williams ji. Oncogene. 2002 Apr 25;21(18):2805-14. doi: 10.1038/sj.onc.1205410. Oncogene. 2002. PMID: 11973639

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