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Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP.
Coles B, Bloodsworth A, Eiserich JP, Coffey MJ, McLoughlin RM, Giddings JC, Lewis MJ, Haslam RJ, Freeman BA, O'Donnell VB. Coles B, et al. Among authors: mcloughlin rm. J Biol Chem. 2002 Feb 22;277(8):5832-40. doi: 10.1074/jbc.M105209200. Epub 2001 Dec 17. J Biol Chem. 2002. PMID: 11748216 Free article.
Interleukin-6 signaling drives fibrosis in unresolved inflammation.
Fielding CA, Jones GW, McLoughlin RM, McLeod L, Hammond VJ, Uceda J, Williams AS, Lambie M, Foster TL, Liao CT, Rice CM, Greenhill CJ, Colmont CS, Hams E, Coles B, Kift-Morgan A, Newton Z, Craig KJ, Williams JD, Williams GT, Davies SJ, Humphreys IR, O'Donnell VB, Taylor PR, Jenkins BJ, Topley N, Jones SA. Fielding CA, et al. Among authors: mcloughlin rm. Immunity. 2014 Jan 16;40(1):40-50. doi: 10.1016/j.immuni.2013.10.022. Epub 2014 Jan 9. Immunity. 2014. PMID: 24412616 Free PMC article.
IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.
McLoughlin RM, Jenkins BJ, Grail D, Williams AS, Fielding CA, Parker CR, Ernst M, Topley N, Jones SA. McLoughlin RM, et al. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9589-94. doi: 10.1073/pnas.0501794102. Epub 2005 Jun 23. Proc Natl Acad Sci U S A. 2005. PMID: 15976028 Free PMC article.
IL-6 regulates neutrophil trafficking during acute inflammation via STAT3.
Fielding CA, McLoughlin RM, McLeod L, Colmont CS, Najdovska M, Grail D, Ernst M, Jones SA, Topley N, Jenkins BJ. Fielding CA, et al. Among authors: mcloughlin rm. J Immunol. 2008 Aug 1;181(3):2189-95. doi: 10.4049/jimmunol.181.3.2189. J Immunol. 2008. PMID: 18641358
Viral IL-6 blocks neutrophil infiltration during acute inflammation.
Fielding CA, McLoughlin RM, Colmont CS, Kovaleva M, Harris DA, Rose-John S, Topley N, Jones SA. Fielding CA, et al. Among authors: mcloughlin rm. J Immunol. 2005 Sep 15;175(6):4024-9. doi: 10.4049/jimmunol.175.6.4024. J Immunol. 2005. PMID: 16148151
96 results