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Nitrolinoleate inhibits platelet activation by attenuating calcium mobilization and inducing phosphorylation of vasodilator-stimulated phosphoprotein through elevation of cAMP.
Coles B, Bloodsworth A, Eiserich JP, Coffey MJ, McLoughlin RM, Giddings JC, Lewis MJ, Haslam RJ, Freeman BA, O'Donnell VB. Coles B, et al. Among authors: lewis mj. J Biol Chem. 2002 Feb 22;277(8):5832-40. doi: 10.1074/jbc.M105209200. Epub 2001 Dec 17. J Biol Chem. 2002. PMID: 11748216 Free article.
Platelet nitrate responsiveness in fasting and postprandial type 2 diabetes.
Anderson RA, Ellis GR, Evans LM, Morris K, Chirkov YY, Horowitz JD, Jackson SK, Rees A, Lewis MJ, Frenneaux MP. Anderson RA, et al. Among authors: lewis mj. Diab Vasc Dis Res. 2005 May;2(2):88-93. doi: 10.3132/dvdr.2005.015. Diab Vasc Dis Res. 2005. PMID: 16305064 Free article.
751 results