Cohen-Williams M - Search Results

1

SCH 57790, a selective muscarinic M(2) receptor antagonist, releases acetylcholine and produces cognitive enhancement in laboratory animals.

Carey GJ, Billard W, Binch H 3rd, Cohen-Williams M, Crosby G, Grzelak M, Guzik H, Kozlowski JA, Lowe DB, Pond AJ, Tedesco RP, Watkins RW, Coffin VL. Carey GJ, et al. Eur J Pharmacol. 2001 Nov 16;431(2):189-200. doi: 10.1016/s0014-2999(01)01440-6. Eur J Pharmacol. 2001. PMID: 11728425

2

Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788.

Lachowicz JE, Duffy RA, Ruperto V, Kozlowski J, Zhou G, Clader J, Billard W, Binch H 3rd, Crosby G, Cohen-Williams M, Strader CD, Coffin V. Lachowicz JE, et al. Life Sci. 2001 Apr 27;68(22-23):2585-92. doi: 10.1016/s0024-3205(01)01056-6. Life Sci. 2001. PMID: 11392630

3

Benzylidene ketal derivatives as M2 muscarinic receptor antagonists.

Boyle CD, Chackalamannil S, Chen LY, Dugar S, Pushpavanam P, Billard W, Binch H 3rd, Crosby G, Cohen-Williams M, Coffin VL, Duffy RA, Ruperto V, Lachowicz JE. Boyle CD, et al. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2727-30. doi: 10.1016/s0960-894x(00)00553-9. Bioorg Med Chem Lett. 2000. PMID: 11133078

4

Metabolic stabilization of benzylidene ketal M(2) muscarinic receptor antagonists via halonaphthoic acid substitution.

Boyle CD, Chackalamannil S, Clader JW, Greenlee WJ, Josien HB, Kaminski JJ, Kozlowski JA, McCombie SW, Nazareno DV, Tagat JR, Wang Y, Zhou G, Billard W, Binch H, Crosby G, Cohen-Williams M, Coffin VL, Cox KA, Grotz DE, Duffy RA, Ruperto V, Lachowicz JE. Boyle CD, et al. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2311-4. doi: 10.1016/s0960-894x(01)00435-8. Bioorg Med Chem Lett. 2001. PMID: 11527721

5

Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists.

Wang Y, Chackalamannil S, Hu Z, Greenlee WJ, Clader J, Boyle CD, Kaminski JJ, Billard W, Binch H 3rd, Crosby G, Ruperto V, Duffy RA, Cohen-Williams M, Coffin VL, Cox KA, Grotz DE, Lachowicz JE. Wang Y, et al. J Med Chem. 2002 Dec 5;45(25):5415-8. doi: 10.1021/jm0255163. J Med Chem. 2002. PMID: 12459007

6

Comparison of apomorphine, amphetamine and dizocilpine disruptions of prepulse inhibition in inbred and outbred mice strains.

Varty GB, Walters N, Cohen-Williams M, Carey GJ. Varty GB, et al. Eur J Pharmacol. 2001 Jul 13;424(1):27-36. doi: 10.1016/s0014-2999(01)01115-3. Eur J Pharmacol. 2001. PMID: 11470257

7

Selective antagonism of the anticonvulsant effects of felbamate by glycine.

Coffin V, Cohen-Williams M, Barnett A. Coffin V, et al. Eur J Pharmacol. 1994 Apr 21;256(2):R9-10. doi: 10.1016/0014-2999(94)90253-4. Eur J Pharmacol. 1994. PMID: 8050461

8

The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists.

Varty GB, Cohen-Williams ME, Morgan CA, Pylak U, Duffy RA, Lachowicz JE, Carey GJ, Coffin VL. Varty GB, et al. Neuropsychopharmacology. 2002 Sep;27(3):371-9. doi: 10.1016/S0893-133X(02)00313-5. Neuropsychopharmacology. 2002. PMID: 12225694

9

The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).

Varty GB, Lu SX, Morgan CA, Cohen-Williams ME, Hodgson RA, Smith-Torhan A, Zhang H, Fawzi AB, Graziano MP, Ho GD, Matasi J, Tulshian D, Coffin VL, Carey GJ. Varty GB, et al. J Pharmacol Exp Ther. 2008 Aug;326(2):672-82. doi: 10.1124/jpet.108.136937. Epub 2008 May 20. J Pharmacol Exp Ther. 2008. PMID: 18492950

10

Cholinergic improvement of a naturally-occurring memory deficit in the young rat.

Smith RD, Kistler MK, Cohen-Williams M, Coffin VL. Smith RD, et al. Brain Res. 1996 Jan 22;707(1):13-21. doi: 10.1016/0006-8993(95)01207-9. Brain Res. 1996. PMID: 8866709

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