Michel S - Search Results

1

Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.

Léonce S, Pérez V, Lambel S, Peyroulan D, Tillequin F, Michel S, Koch M, Pfeiffer B, Atassi G, Hickman JA, Pierré A. Léonce S, et al. Among authors: michel s. Mol Pharmacol. 2001 Dec;60(6):1383-91. doi: 10.1124/mol.60.6.1383. Mol Pharmacol. 2001. PMID: 11723246

2

Influence of the stereoisomeric position of the reactive acetate groups of the benzo[b]acronycine derivative S23906-1 on its DNA alkylation, helix-opening, cytotoxic, and antitumor activities.

Depauw S, Gaslonde T, Léonce S, Kraus-Berthier L, Laine W, Lenglet G, Chiaroni A, Pfeiffer B, Bailly C, Michel S, Tillequin F, Pierré A, David-Cordonnier MH. Depauw S, et al. Among authors: michel s. Mol Pharmacol. 2009 Dec;76(6):1172-85. doi: 10.1124/mol.109.057554. Epub 2009 Sep 14. Mol Pharmacol. 2009. PMID: 19752199

3

Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors.

Guilbaud N, Kraus-Berthier L, Meyer-Losic F, Malivet V, Chacun C, Jan M, Tillequin F, Michel S, Koch M, Pfeiffer B, Atassi G, Hickman J, Pierré A. Guilbaud N, et al. Among authors: michel s. Clin Cancer Res. 2001 Aug;7(8):2573-80. Clin Cancer Res. 2001. PMID: 11489841

4

Structure-activity relationships in the acronycine series.

Michel S, Seguin E, Tillequin F. Michel S, et al. Curr Med Chem. 2002 Sep;9(18):1689-700. doi: 10.2174/0929867023369213. Curr Med Chem. 2002. PMID: 12171551 Review.

5

Synthesis of 6-dialkylaminoalkylamino pyrano[2,3-c]acridones and benzo[b]pyrano[3,2-h]acridones: soluble acronycine analogues with increased cytotoxic activity.

Costes N, Elomri A, Dufat H, Michel S, Seguin E, Koch M, Tillequin F, Pfeiffer B, Renard P, Léonce S, Pierré A. Costes N, et al. Among authors: michel s. Oncol Res. 2003;13(4):191-7. Oncol Res. 2003. PMID: 12659419

6

Covalent binding to glutathione of the DNA-alkylating antitumor agent, S23906-1.

David-Cordonnier MH, Laine W, Joubert A, Tardy C, Goossens JF, Kouach M, Briand G, Thi Mai HD, Michel S, Tillequin F, Koch M, Leonce S, Pierre A, Bailly C. David-Cordonnier MH, et al. Among authors: michel s. Eur J Biochem. 2003 Jul;270(13):2848-59. doi: 10.1046/j.1432-1033.2003.03663.x. Eur J Biochem. 2003. PMID: 12823555 Free article.

7

Synthesis and cytotoxic and antitumor activity of 1,2-dihydroxy-1,2-dihydrobenzo[b]acronycine diacid hemiesters and carbamates.

Doan Thi Mai H, Gaslonde T, Michel S, Koch M, Tillequin F, Pfeiffer B, Renard P, Kraus-Berthier L, Léonce S, Pierré A. Doan Thi Mai H, et al. Among authors: michel s. Chem Pharm Bull (Tokyo). 2004 Mar;52(3):293-7. doi: 10.1248/cpb.52.293. Chem Pharm Bull (Tokyo). 2004. PMID: 14993749 Free article.

8

Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: unique consequences of a novel DNA-bonding mechanism.

David-Cordonnier MH, Laine W, Lansiaux A, Rosu F, Colson P, de Pauw E, Michel S, Tillequin F, Koch M, Hickman JA, Pierré A, Bailly C. David-Cordonnier MH, et al. Among authors: michel s. Mol Cancer Ther. 2005 Jan;4(1):71-80. Mol Cancer Ther. 2005. PMID: 15657355

9

Synthesis and cytotoxic activity of dimeric analogs of acronycine in the benzo[b]pyrano[3,2-h]acridin-7-one series.

Gaslonde T, Michel S, Koch M, Pfeiffer B, Léonce S, Pierré A, Tillequin F. Gaslonde T, et al. Among authors: michel s. Chem Pharm Bull (Tokyo). 2007 May;55(5):734-8. doi: 10.1248/cpb.55.734. Chem Pharm Bull (Tokyo). 2007. PMID: 17473459 Free article.

10

Structure-activity relationships in the acronycine and benzo[b]acronycine series: role of the pyran ring.

Do Q, Thi Mai HD, Gaslonde T, Pfeiffer B, Léonce S, Pierré A, Michel S, Tillequin F, Dufat H. Do Q, et al. Among authors: michel s. Eur J Med Chem. 2008 Dec;43(12):2677-87. doi: 10.1016/j.ejmech.2008.01.033. Epub 2008 Feb 3. Eur J Med Chem. 2008. PMID: 18342404

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