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Two sites in the MAPT region confer genetic risk for Guam ALS/PDC and dementia.
Sundar PD, Yu CE, Sieh W, Steinbart E, Garruto RM, Oyanagi K, Craig UK, Bird TD, Wijsman EM, Galasko DR, Schellenberg GD. Sundar PD, et al. Among authors: garruto rm. Hum Mol Genet. 2007 Feb 1;16(3):295-306. doi: 10.1093/hmg/ddl463. Epub 2006 Dec 21. Hum Mol Genet. 2007. PMID: 17185385
ALS and PDC of Guam: forty-year follow-up.
Plato CC, Galasko D, Garruto RM, Plato M, Gamst A, Craig UK, Torres JM, Wiederholt W. Plato CC, et al. Among authors: garruto rm. Neurology. 2002 Mar 12;58(5):765-73. doi: 10.1212/wnl.58.5.765. Neurology. 2002. PMID: 11889241
Tau is a candidate gene for chromosome 17 frontotemporal dementia.
Poorkaj P, Bird TD, Wijsman E, Nemens E, Garruto RM, Anderson L, Andreadis A, Wiederholt WC, Raskind M, Schellenberg GD. Poorkaj P, et al. Among authors: garruto rm. Ann Neurol. 1998 Jun;43(6):815-25. doi: 10.1002/ana.410430617. Ann Neurol. 1998. PMID: 9629852
189 results