Neumeyer JL - Search Results

1

Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan.

Neumeyer JL, Gu XH, van Vliet LA, DeNunzio NJ, Rusovici DE, Cohen DJ, Negus SS, Mello NK, Bidlack JM. Neumeyer JL, et al. Bioorg Med Chem Lett. 2001 Oct 22;11(20):2735-40. doi: 10.1016/s0960-894x(01)00543-1. Bioorg Med Chem Lett. 2001. PMID: 11591513

2

Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors.

Neumeyer JL, Zhang A, Xiong W, Gu XH, Hilbert JE, Knapp BI, Negus SS, Mello NK, Bidlack JM. Neumeyer JL, et al. J Med Chem. 2003 Nov 20;46(24):5162-70. doi: 10.1021/jm030139v. J Med Chem. 2003. PMID: 14613319

3

10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors.

Zhang A, Xiong W, Bidlack JM, Hilbert JE, Knapp BI, Wentland MP, Neumeyer JL. Zhang A, et al. Among authors: neumeyer jl. J Med Chem. 2004 Jan 1;47(1):165-74. doi: 10.1021/jm0304156. J Med Chem. 2004. PMID: 14695830

4

2-aminothiazole-derived opioids. Bioisosteric replacement of phenols.

Zhang A, Xiong W, Hilbert JE, DeVita EK, Bidlack JM, Neumeyer JL. Zhang A, et al. Among authors: neumeyer jl. J Med Chem. 2004 Apr 8;47(8):1886-8. doi: 10.1021/jm049978n. J Med Chem. 2004. PMID: 15055988

5

An investigation of the N-demethylation of 3-deoxymorphine and the affinity of the alkylation products to mu, delta, and kappa receptors.

Csutoras C, Zhang A, Bidlack JM, Neumeyer JL. Csutoras C, et al. Among authors: neumeyer jl. Bioorg Med Chem. 2004 May 15;12(10):2687-90. doi: 10.1016/j.bmc.2004.03.011. Bioorg Med Chem. 2004. PMID: 15110850

6

Synthesis and preliminary in vitro investigation of bivalent ligands containing homo- and heterodimeric pharmacophores at mu, delta, and kappa opioid receptors.

Peng X, Knapp BI, Bidlack JM, Neumeyer JL. Peng X, et al. Among authors: neumeyer jl. J Med Chem. 2006 Jan 12;49(1):256-62. doi: 10.1021/jm050577x. J Med Chem. 2006. PMID: 16392810

7

New opioid designed multiple ligand from Dmt-Tic and morphinan pharmacophores.

Neumeyer JL, Peng X, Knapp BI, Bidlack JM, Lazarus LH, Salvadori S, Trapella C, Balboni G. Neumeyer JL, et al. J Med Chem. 2006 Sep 7;49(18):5640-3. doi: 10.1021/jm0605785. J Med Chem. 2006. PMID: 16942040 Free PMC article.

8

High-affinity carbamate analogues of morphinan at opioid receptors.

Peng X, Knapp BI, Bidlack JM, Neumeyer JL. Peng X, et al. Among authors: neumeyer jl. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1508-11. doi: 10.1016/j.bmcl.2007.01.013. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17276685 Free PMC article.

9

Pharmacological properties of bivalent ligands containing butorphan linked to nalbuphine, naltrexone, and naloxone at mu, delta, and kappa opioid receptors.

Peng X, Knapp BI, Bidlack JM, Neumeyer JL. Peng X, et al. Among authors: neumeyer jl. J Med Chem. 2007 May 3;50(9):2254-8. doi: 10.1021/jm061327z. Epub 2007 Apr 4. J Med Chem. 2007. PMID: 17407276 Free PMC article.

10

In-vitro investigation of oxazol and urea analogues of morphinan at opioid receptors.

Peng X, Knapp BI, Bidlack JM, Neumeyer JL. Peng X, et al. Among authors: neumeyer jl. Bioorg Med Chem. 2007 Jun 15;15(12):4106-12. doi: 10.1016/j.bmc.2007.03.076. Epub 2007 Mar 30. Bioorg Med Chem. 2007. PMID: 17433695 Free PMC article.

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