Eigenbrot C - Search Results

1

A novel exosite on coagulation factor VIIa and its molecular interactions with a new class of peptide inhibitors.

Roberge M, Santell L, Dennis MS, Eigenbrot C, Dwyer MA, Lazarus RA. Roberge M, et al. Among authors: eigenbrot c. Biochemistry. 2001 Aug 14;40(32):9522-31. doi: 10.1021/bi010592d. Biochemistry. 2001. PMID: 11583151

S., Eigenbrot, C., Skelton, N. J., Ultsch, M. H., Santell, L., Dwyer, M. A., O'Connell, M. P., and Lazarus, R. ...Analysis of the mutagenesis data is presented in the context of a crystal structure of A-183 in complex with a version of zymogen FVII [Eigenbrot …

S., Eigenbrot, C., Skelton, N. J., Ultsch, M. H., Santell, L., Dwyer, M. A., O'Connell, M. P., and Lazarus, R. ...Analysis of …

2

Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments.

Kelley RF, O'Connell MP, Carter P, Presta L, Eigenbrot C, Covarrubias M, Snedecor B, Bourell JH, Vetterlein D. Kelley RF, et al. Among authors: eigenbrot c. Biochemistry. 1992 Jun 23;31(24):5434-41. doi: 10.1021/bi00139a003. Biochemistry. 1992. PMID: 1351741

3

Neutron structure of subtilisin BPN': effects of chemical environment on hydrogen-bonding geometries and the pattern of hydrogen-deuterium exchange in secondary structure elements.

Kossiakoff AA, Ultsch M, White S, Eigenbrot C. Kossiakoff AA, et al. Among authors: eigenbrot c. Biochemistry. 1991 Feb 5;30(5):1211-21. doi: 10.1021/bi00219a008. Biochemistry. 1991. PMID: 1991100

4

X-ray crystal structure of the protease inhibitor domain of Alzheimer's amyloid beta-protein precursor.

Hynes TR, Randal M, Kennedy LA, Eigenbrot C, Kossiakoff AA. Hynes TR, et al. Among authors: eigenbrot c. Biochemistry. 1990 Oct 30;29(43):10018-22. doi: 10.1021/bi00495a002. Biochemistry. 1990. PMID: 2125487

5

Peptide exosite inhibitors of factor VIIa as anticoagulants.

Dennis MS, Eigenbrot C, Skelton NJ, Ultsch MH, Santell L, Dwyer MA, O'Connell MP, Lazarus RA. Dennis MS, et al. Among authors: eigenbrot c. Nature. 2000 Mar 30;404(6777):465-70. doi: 10.1038/35006574. Nature. 2000. PMID: 10761907

6

The tissue factor region that interacts with substrates factor IX and Factor X.

Kirchhofer D, Lipari MT, Moran P, Eigenbrot C, Kelley RF. Kirchhofer D, et al. Among authors: eigenbrot c. Biochemistry. 2000 Jun 27;39(25):7380-7. doi: 10.1021/bi000182+. Biochemistry. 2000. PMID: 10858285

7

Epitope location on tissue factor determines the anticoagulant potency of monoclonal anti-tissue factor antibodies.

Kirchhofer D, Moran P, Chiang N, Kim J, Riederer MA, Eigenbrot C, Kelley RF. Kirchhofer D, et al. Among authors: eigenbrot c. Thromb Haemost. 2000 Dec;84(6):1072-81. Thromb Haemost. 2000. PMID: 11154116

8

The tissue factor region that interacts with factor Xa in the activation of factor VII.

Kirchhofer D, Eigenbrot C, Lipari MT, Moran P, Peek M, Kelley RF. Kirchhofer D, et al. Among authors: eigenbrot c. Biochemistry. 2001 Jan 23;40(3):675-82. doi: 10.1021/bi002013v. Biochemistry. 2001. PMID: 11170384

9

The factor VII zymogen structure reveals reregistration of beta strands during activation.

Eigenbrot C, Kirchhofer D, Dennis MS, Santell L, Lazarus RA, Stamos J, Ultsch MH. Eigenbrot C, et al. Structure. 2001 Jul 3;9(7):627-36. doi: 10.1016/s0969-2126(01)00624-4. Structure. 2001. PMID: 11470437 Free article.

10

New insight into how tissue factor allosterically regulates factor VIIa.

Eigenbrot C, Kirchhofer D. Eigenbrot C, et al. Trends Cardiovasc Med. 2002 Jan;12(1):19-26. doi: 10.1016/s1050-1738(01)00139-6. Trends Cardiovasc Med. 2002. PMID: 11796240 Review.

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