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Arginine 52 and histidine 54 located in a conserved amino-terminal hydrophobic region (LX2-R52-G-H54-X3-V-L) are important amino acids for the functional and structural integrity of the human liver UDP-glucuronosyltransferase UGT1*6.
Senay C, Ouzzine M, Battaglia E, Pless D, Cano V, Burchell B, Radominska A, Magdalou J, Fournel-Gigleux S. Senay C, et al. Among authors: battaglia e. Mol Pharmacol. 1997 Mar;51(3):406-13. Mol Pharmacol. 1997. PMID: 9058595
201 results