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Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.
Rastogi R, Jiang Z, Ahmad N, Rosati R, Liu Y, Beuret L, Monks R, Charron J, Birnbaum MJ, Samavati L. Rastogi R, et al. Among authors: charron j. J Biol Chem. 2013 Nov 22;288(47):33966-33977. doi: 10.1074/jbc.M113.492702. Epub 2013 Oct 14. J Biol Chem. 2013. PMID: 24126911 Free PMC article.
Mek2 is dispensable for mouse growth and development.
Bélanger LF, Roy S, Tremblay M, Brott B, Steff AM, Mourad W, Hugo P, Erikson R, Charron J. Bélanger LF, et al. Among authors: charron j. Mol Cell Biol. 2003 Jul;23(14):4778-87. doi: 10.1128/MCB.23.14.4778-4787.2003. Mol Cell Biol. 2003. PMID: 12832465 Free PMC article.
Fine-tuning of MEK signaling is pivotal for limiting B and T cell activation.
Houde N, Beuret L, Bonaud A, Fortier-Beaulieu SP, Truchon-Landry K, Aoidi R, Pic É, Alouche N, Rondeau V, Schlecht-Louf G, Balabanian K, Espéli M, Charron J. Houde N, et al. Among authors: charron j. Cell Rep. 2022 Jan 11;38(2):110223. doi: 10.1016/j.celrep.2021.110223. Cell Rep. 2022. PMID: 35021072 Free article.
143 results