Hughes DE - Search Results

1

Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver.

Yu S, Cao WQ, Kashireddy P, Meyer K, Jia Y, Hughes DE, Tan Y, Feng J, Yeldandi AV, Rao MS, Costa RH, Gonzalez FJ, Reddy JK. Yu S, et al. Among authors: hughes de. J Biol Chem. 2001 Nov 9;276(45):42485-91. doi: 10.1074/jbc.M106480200. Epub 2001 Sep 10. J Biol Chem. 2001. PMID: 11551940 Free article.

2

Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage.

Hughes DE, Stolz DB, Yu S, Tan Y, Reddy JK, Watkins SC, Diehl AM, Costa RH. Hughes DE, et al. Hepatology. 2003 Jun;37(6):1414-24. doi: 10.1053/jhep.2003.50253. Hepatology. 2003. PMID: 12774021

3

Stability of the hepatocyte nuclear factor 6 transcription factor requires acetylation by the CREB-binding protein coactivator.

Rausa FM 3rd, Hughes DE, Costa RH. Rausa FM 3rd, et al. Among authors: hughes de. J Biol Chem. 2004 Oct 8;279(41):43070-6. doi: 10.1074/jbc.M407472200. Epub 2004 Aug 9. J Biol Chem. 2004. PMID: 15304484 Free article.

4

Functional characterization of evolutionarily conserved DNA regions in forkhead box f1 gene locus.

Kim IM, Zhou Y, Ramakrishna S, Hughes DE, Solway J, Costa RH, Kalinichenko VV. Kim IM, et al. Among authors: hughes de. J Biol Chem. 2005 Nov 11;280(45):37908-16. doi: 10.1074/jbc.M506531200. Epub 2005 Sep 6. J Biol Chem. 2005. PMID: 16144835 Free article.

5

Increased expression of hepatocyte nuclear factor 6 stimulates hepatocyte proliferation during mouse liver regeneration.

Tan Y, Yoshida Y, Hughes DE, Costa RH. Tan Y, et al. Among authors: hughes de. Gastroenterology. 2006 Apr;130(4):1283-300. doi: 10.1053/j.gastro.2006.01.010. Gastroenterology. 2006. PMID: 16618419 Free PMC article.

6

FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness.

Wang IC, Chen YJ, Hughes DE, Ackerson T, Major ML, Kalinichenko VV, Costa RH, Raychaudhuri P, Tyner AL, Lau LF. Wang IC, et al. Among authors: hughes de. J Biol Chem. 2008 Jul 25;283(30):20770-8. doi: 10.1074/jbc.M709892200. Epub 2008 Jun 4. J Biol Chem. 2008. PMID: 18524773 Free PMC article.

7

Adenovirus-mediated increase in HNF-3beta or HNF-3alpha shows differences in levels of liver glycogen and gene expression.

Tan Y, Hughes D, Wang X, Costa RH. Tan Y, et al. Hepatology. 2002 Jan;35(1):30-9. doi: 10.1053/jhep.2002.30317. Hepatology. 2002. PMID: 11786957

8

Atypical mouse cerebellar development is caused by ectopic expression of the forkhead box transcription factor HNF-3beta.

Zhou H, Hughes DE, Major ML, Yoo K, Pesold C, Costa RH. Zhou H, et al. Among authors: hughes de. Gene Expr. 2001;9(4-5):217-36. doi: 10.3727/000000001783992597. Gene Expr. 2001. PMID: 11444531 Free PMC article.

9

C/EBPalpha and HNF6 protein complex formation stimulates HNF6-dependent transcription by CBP coactivator recruitment in HepG2 cells.

Yoshida Y, Hughes DE, Rausa FM 3rd, Kim IM, Tan Y, Darlington GJ, Costa RH. Yoshida Y, et al. Among authors: hughes de. Hepatology. 2006 Feb;43(2):276-86. doi: 10.1002/hep.21044. Hepatology. 2006. PMID: 16440369 Free PMC article.

10

Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1.

Radhakrishnan SK, Bhat UG, Hughes DE, Wang IC, Costa RH, Gartel AL. Radhakrishnan SK, et al. Among authors: hughes de. Cancer Res. 2006 Oct 1;66(19):9731-5. doi: 10.1158/0008-5472.CAN-06-1576. Cancer Res. 2006. PMID: 17018632

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