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Page 1
Design and synthesis of glycolic and mandelic acid derivatives as factor Xa inhibitors.
Su T, Wu Y, Doughan B, Kane-Maguire K, Marlowe CK, Kanter JP, Woolfrey J, Huang B, Wong P, Sinha U, Park G, Malinowski J, Hollenbach S, Scarborough RM, Zhu BY. Su T, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2279-82. doi: 10.1016/s0960-894x(01)00447-4. Bioorg Med Chem Lett. 2001. PMID: 11527714
Design, synthesis, and SAR of substituted acrylamides as factor Xa inhibitors.
Song Y, Clizbe L, Bhakta C, Teng W, Li W, Wu Y, Jia ZJ, Zhang P, Wang L, Doughan B, Su T, Kanter J, Woolfrey J, Wong P, Huang B, Tran K, Sinha U, Park G, Reed A, Malinowski J, Hollenbach S, Scarborough RM, Zhu BY. Song Y, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1511-5. doi: 10.1016/s0960-894x(02)00199-3. Bioorg Med Chem Lett. 2002. PMID: 12031331
Design, synthesis and biological activity of novel non-amidine factor Xa inhibitors. Part 1: P(1) structure-activity relationships of the substituted 1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides.
Jia ZJ, Wu Y, Huang W, Goldman E, Zhang P, Woolfrey J, Wong P, Huang B, Sinha U, Park G, Reed A, Scarborough RM, Zhu BY. Jia ZJ, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1651-5. doi: 10.1016/s0960-894x(02)00239-1. Bioorg Med Chem Lett. 2002. PMID: 12039583
Design and synthesis of factor Xa inhibitors and their prodrugs.
Song Y, Clizbe L, Bhakta C, Teng W, Wong P, Huang B, Tran K, Sinha U, Park G, Reed A, Scarborough RM, Zhu BY. Song Y, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2003 Jan 20;13(2):297-300. doi: 10.1016/s0960-894x(02)00921-6. Bioorg Med Chem Lett. 2003. PMID: 12482444
Design, synthesis and structure-activity relationships of benzoxazinone-based factor Xa inhibitors.
Huang W, Zhang P, Zuckett JF, Wang L, Woolfrey J, Song Y, Jia ZJ, Clizbe LA, Su T, Tran K, Huang B, Wong P, Sinha U, Park G, Reed A, Malinowski J, Hollenbach SJ, Scarborough RM, Zhu BY. Huang W, et al. Among authors: scarborough rm. Bioorg Med Chem Lett. 2003 Feb 10;13(3):561-6. doi: 10.1016/s0960-894x(02)00927-7. Bioorg Med Chem Lett. 2003. PMID: 12565972
Inhibition of purified factor Xa amidolytic activity may not be predictive of inhibition of in vivo thrombosis: implications for identification of therapeutically active inhibitors.
Sinha U, Lin PH, Edwards ST, Wong PW, Zhu B, Scarborough RM, Su T, Jia ZJ, Song Y, Zhang P, Clizbe L, Park G, Reed A, Hollenbach SJ, Malinowski J, Arfsten AE. Sinha U, et al. Among authors: scarborough rm. Arterioscler Thromb Vasc Biol. 2003 Jun 1;23(6):1098-104. doi: 10.1161/01.ATV.0000077248.22632.88. Epub 2003 May 15. Arterioscler Thromb Vasc Biol. 2003. PMID: 12750119
95 results