Furet P - Search Results

1

Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction.

García-Echeverría C, Furet P, Chène P. García-Echeverría C, et al. Among authors: furet p. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2161-4. doi: 10.1016/s0960-894x(01)00394-8. Bioorg Med Chem Lett. 2001. PMID: 11514160

2

Dianilinophthalimides: potent and selective, ATP-competitive inhibitors of the EGF-receptor protein tyrosine kinase.

Trinks U, Buchdunger E, Furet P, Kump W, Mett H, Meyer T, Müller M, Regenass U, Rihs G, Lydon N, et al. Trinks U, et al. Among authors: furet p. J Med Chem. 1994 Apr 1;37(7):1015-27. doi: 10.1021/jm00033a019. J Med Chem. 1994. PMID: 8151612

3

Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode.

Rahuel J, Gay B, Erdmann D, Strauss A, Garcia-Echeverría C, Furet P, Caravatti G, Fretz H, Schoepfer J, Grütter MG. Rahuel J, et al. Among authors: furet p. Nat Struct Biol. 1996 Jul;3(7):586-9. doi: 10.1038/nsb0796-586. Nat Struct Biol. 1996. PMID: 8673601 No abstract available.

4

Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands.

Gay B, Furet P, García-Echeverría C, Rahuel J, Chène P, Fretz H, Schoepfer J, Caravatti G. Gay B, et al. Among authors: furet p. Biochemistry. 1997 May 13;36(19):5712-8. doi: 10.1021/bi962642y. Biochemistry. 1997. PMID: 9153411

5

Discovery of 3-aminobenzyloxycarbonyl as an N-terminal group conferring high affinity to the minimal phosphopeptide sequence recognized by the Grb2-SH2 domain.

Furet P, Gay B, García-Echeverría C, Rahuel J, Fretz H, Schoepfer J, Caravatti G. Furet P, et al. J Med Chem. 1997 Oct 24;40(22):3551-6. doi: 10.1021/jm9702185. J Med Chem. 1997. PMID: 9357522

6

Potent antagonists of the SH2 domain of Grb2: optimization of the X+1 position of 3-amino-Z-Tyr(PO3H2)-X+1-Asn-NH2.

García-Echeverría C, Furet P, Gay B, Fretz H, Rahuel J, Schoepfer J, Caravatti G. García-Echeverría C, et al. Among authors: furet p. J Med Chem. 1998 May 21;41(11):1741-4. doi: 10.1021/jm970856n. J Med Chem. 1998. PMID: 9599224 No abstract available.

7

Structural basis for the high affinity of amino-aromatic SH2 phosphopeptide ligands.

Rahuel J, García-Echeverría C, Furet P, Strauss A, Caravatti G, Fretz H, Schoepfer J, Gay B. Rahuel J, et al. Among authors: furet p. J Mol Biol. 1998 Jun 19;279(4):1013-22. doi: 10.1006/jmbi.1998.1790. J Mol Biol. 1998. PMID: 9642078

8

Structure-based design and synthesis of high affinity tripeptide ligands of the Grb2-SH2 domain.

Furet P, Gay B, Caravatti G, García-Echeverría C, Rahuel J, Schoepfer J, Fretz H. Furet P, et al. J Med Chem. 1998 Aug 27;41(18):3442-9. doi: 10.1021/jm980159a. J Med Chem. 1998. PMID: 9719597

9

Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain.

Schoepfer J, Gay B, Caravatti G, Garcia-Echeverria C, Fretz H, Rahuel J, Furet P. Schoepfer J, et al. Among authors: furet p. Bioorg Med Chem Lett. 1998 Oct 20;8(20):2865-70. doi: 10.1016/s0960-894x(98)00513-7. Bioorg Med Chem Lett. 1998. PMID: 9873638

10

2,6,9-trisubstituted purines: optimization towards highly potent and selective CDK1 inhibitors.

Imbach P, Capraro HG, Furet P, Mett H, Meyer T, Zimmermann J. Imbach P, et al. Among authors: furet p. Bioorg Med Chem Lett. 1999 Jan 4;9(1):91-6. doi: 10.1016/s0960-894x(98)00691-x. Bioorg Med Chem Lett. 1999. PMID: 9990463

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