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Identification of a signal necessary for initiation of reverse transcription of the hepadnavirus genome.
Seeger C, Maragos J. Seeger C, et al. J Virol. 1991 Oct;65(10):5190-5. doi: 10.1128/JVI.65.10.5190-5195.1991. J Virol. 1991. PMID: 1895379 Free PMC article.
Reverse transcription of the hepadnavirus genome initiates near the 3' end of the RNA template and has previously been shown to depend on sequences flanking the initiation site for DNA synthesis (C. Seeger and J. Maragos, J. Virol. 64:16-23, 1990). DNA synthesis lea …
Reverse transcription of the hepadnavirus genome initiates near the 3' end of the RNA template and has previously been shown to depend on se …
Expression of infectious woodchuck hepatitis virus in murine and avian fibroblasts.
Seeger C, Baldwin B, Tennant BC. Seeger C, et al. J Virol. 1989 Nov;63(11):4665-9. doi: 10.1128/JVI.63.11.4665-4669.1989. J Virol. 1989. PMID: 2795716 Free PMC article.
For this purpose, we assayed a previously constructed chimera between sequences of the cytomegalovirus immediate-early promoter-enhancer region and woodchuck hepatitis virus (WHV) (C. Seeger and J. Maragos, J. Virol. 63:1907-1915, 1989) for its ability to direct the …
For this purpose, we assayed a previously constructed chimera between sequences of the cytomegalovirus immediate-early promoter-enhancer reg …
Reverse transcription in hepatitis B viruses is primed by a tyrosine residue of the polymerase.
Zoulim F, Seeger C. Zoulim F, et al. Among authors: seeger c. J Virol. 1994 Jan;68(1):6-13. doi: 10.1128/JVI.68.1.6-13.1994. J Virol. 1994. PMID: 7504742 Free PMC article.
Recently, the reverse transcriptase of a hepadnavirus has been shown to prime RNA-directed DNA synthesis from an internal site of the polypeptide (G.H. Wang and C. Seeger, Cell 71:663-670, 1992). In this report we demonstrate that a tyrosine residue of the polymeras …
Recently, the reverse transcriptase of a hepadnavirus has been shown to prime RNA-directed DNA synthesis from an internal site of the polype …
Role of RNA in enzymatic activity of the reverse transcriptase of hepatitis B viruses.
Wang GH, Zoulim F, Leber EH, Kitson J, Seeger C. Wang GH, et al. Among authors: seeger c. J Virol. 1994 Dec;68(12):8437-42. doi: 10.1128/JVI.68.12.8437-8442.1994. J Virol. 1994. PMID: 7525990 Free PMC article.
Previously, we demonstrated that the protein-priming activity of the polymerase requires a viral RNA segment, termed epsilon, which serves as a template for the synthesis of a short DNA oligomer that is covalently attached to the reverse transcriptase (G.-H. Wang and C. …
Previously, we demonstrated that the protein-priming activity of the polymerase requires a viral RNA segment, termed epsilon, which serves a …
Novel mechanism for reverse transcription in hepatitis B viruses.
Wang GH, Seeger C. Wang GH, et al. Among authors: seeger c. J Virol. 1993 Nov;67(11):6507-12. doi: 10.1128/JVI.67.11.6507-6512.1993. J Virol. 1993. PMID: 7692081 Free PMC article.
However, in hepatitis B viruses the viral polymerase itself acts as a primer for reverse transcription (G.-H. Wang and C. Seeger, Cell 71:663-670, 1992). We have now demonstrated that in order to prime DNA synthesis, the polymerase binds to an RNA hairpin, which the …
However, in hepatitis B viruses the viral polymerase itself acts as a primer for reverse transcription (G.-H. Wang and C. Seeger …
104 results