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Weak TCR stimulation induces a calcium signal that triggers IL-4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN-gamma production.
Badou A, Savignac M, Moreau M, Leclerc C, Foucras G, Cassar G, Paulet P, Lagrange D, Druet P, Guéry JC, Pelletier L. Badou A, et al. Among authors: lagrange d. Eur J Immunol. 2001 Aug;31(8):2487-96. doi: 10.1002/1521-4141(200108)31:8<2487::aid-immu2487>3.0.co;2-l. Eur J Immunol. 2001. PMID: 11500833 Free article.
Rat chromosome 9 bears a major susceptibility locus for IgE response.
Mas M, Subra JF, Lagrange D, Pilipenko-Appolinaire S, Kermarrec N, Gauguier D, Druet P, Fournié GJ. Mas M, et al. Among authors: lagrange d. Eur J Immunol. 2000 Jun;30(6):1698-705. doi: 10.1002/1521-4141(200006)30:6<1698::AID-IMMU1698>3.0.CO;2-F. Eur J Immunol. 2000. PMID: 10898507 Free article.
Studies of congenic lines in the Brown Norway rat model of Th2-mediated immunopathological disorders show that the aurothiopropanol sulfonate-induced immunological disorder (Aiid3) locus on chromosome 9 plays a major role compared to Aiid2 on chromosome 10.
Mas M, Cavaillès P, Colacios C, Subra JF, Lagrange D, Calise M, Christen MO, Druet P, Pelletier L, Gauguier D, Fournié GJ. Mas M, et al. Among authors: lagrange d. J Immunol. 2004 May 15;172(10):6354-61. doi: 10.4049/jimmunol.172.10.6354. J Immunol. 2004. PMID: 15128826
The rat Toxo1 locus directs toxoplasmosis outcome and controls parasite proliferation and spreading by macrophage-dependent mechanisms.
Cavaillès P, Sergent V, Bisanz C, Papapietro O, Colacios C, Mas M, Subra JF, Lagrange D, Calise M, Appolinaire S, Faraut T, Druet P, Saoudi A, Bessieres MH, Pipy B, Cesbron-Delauw MF, Fournié GJ. Cavaillès P, et al. Among authors: lagrange d. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):744-9. doi: 10.1073/pnas.0506643103. Epub 2006 Jan 6. Proc Natl Acad Sci U S A. 2006. PMID: 16407112 Free PMC article.
39 results