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Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichloroisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4.
Lin LS, Lanza T, Jewell JP, Liu P, Jones C, Kieczykowski GR, Treonze K, Si Q, Manior S, Koo G, Tong X, Wang J, Schuelke A, Pivnichny J, Wang R, Raab C, Vincent S, Davies P, Maccoss M, Mumford RA, Hagmann WK. Lin LS, et al. Among authors: schuelke a. J Med Chem. 2009 Jun 11;52(11):3449-52. doi: 10.1021/jm900257b. J Med Chem. 2009. PMID: 19441819
Measurement of the rate of nu(e) + d --> p + p + e(-) interactions produced by (8)B solar neutrinos at the Sudbury Neutrino Observatory.
Ahmad QR, Allen RC, Andersen TC, Anglin JD, Bühler G, Barton JC, Beier EW, Bercovitch M, Bigu J, Biller S, Black RA, Blevis I, Boardman RJ, Boger J, Bonvin E, Boulay MG, Bowler MG, Bowles TJ, Brice SJ, Browne MC, Bullard TV, Burritt TH, Cameron K, Cameron J, Chan YD, Chen M, Chen HH, Chen X, Chon MC, Cleveland BT, Clifford ET, Cowan JH, Cowen DF, Cox GA, Dai Y, Dai X, Dalnoki-Veress F, Davidson WF, Doe PJ, Doucas G, Dragowsky MR, Duba CA, Duncan FA, Dunmore J, Earle ED, Elliott SR, Evans HC, Ewan GT, Farine J, Fergani H, Ferraris AP, Ford RJ, Fowler MM, Frame K, Frank ED, Frati W, Germani JV, Gil S, Goldschmidt A, Grant DR, Hahn RL, Hallin AL, Hallman ED, Hamer A, Hamian AA, Haq RU, Hargrove CK, Harvey PJ, Hazama R, Heaton R, Heeger KM, Heintzelman WJ, Heise J, Helmer RL, Hepburn JD, Heron H, Hewett J, Hime A, Howe M, Hykawy JG, Isaac MC, Jagam P, Jelley NA, Jillings C, Jonkmans G, Karn J, Keener PT, Kirch K, Klein JR, Knox AB, Komar RJ, Kouzes R, Kutter T, Kyba CC, Law J, Lawson IT, Lay M, Lee HW, Lesko KT, Leslie JR, Levine I, Locke W, Lowry MM, Luoma S, Lyon J, Majerus S, Mak HB, Marino AD, McCauley N, McDonald AB, McDonald DS, McFarlane K, McGregor G, McLatchie W, Meijer Drees… See abstract for full author list ➔ Ahmad QR, et al. Among authors: schuelke a. Phys Rev Lett. 2001 Aug 13;87(7):071301. doi: 10.1103/PhysRevLett.87.071301. Epub 2001 Jul 25. Phys Rev Lett. 2001. PMID: 11497878