Eckman CB - Search Results

1

High throughput screens for the identification of compounds that alter the accumulation of the Alzheimer's amyloid beta peptide (Abeta).

Haugabook SJ, Yager DM, Eckman EA, Golde TE, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: eckman ea, eckman cb. J Neurosci Methods. 2001 Jul 30;108(2):171-9. doi: 10.1016/s0165-0270(01)00388-0. J Neurosci Methods. 2001. PMID: 11478976

2

Natural product extracts that reduce accumulation of the Alzheimer's amyloid beta peptide: selective reduction in A beta42.

Yager D, Watson M, Healy B, Eckman EA, Eckman CB. Yager D, et al. Among authors: eckman ea, eckman cb. J Mol Neurosci. 2002 Aug-Oct;19(1-2):129-33. doi: 10.1007/s12031-002-0023-5. J Mol Neurosci. 2002. PMID: 12212770

3

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme.

Eckman EA, Watson M, Marlow L, Sambamurti K, Eckman CB. Eckman EA, et al. Among authors: eckman cb. J Biol Chem. 2003 Jan 24;278(4):2081-4. doi: 10.1074/jbc.C200642200. Epub 2002 Dec 2. J Biol Chem. 2003. PMID: 12464614 Free article.

4

Reductions in levels of the Alzheimer's amyloid beta peptide after oral administration of ginsenosides.

Chen F, Eckman EA, Eckman CB. Chen F, et al. Among authors: eckman ea, eckman cb. FASEB J. 2006 Jun;20(8):1269-71. doi: 10.1096/fj.05-5530fje. Epub 2006 Apr 24. FASEB J. 2006. PMID: 16636099

5

An update on the amyloid hypothesis.

Eckman CB, Eckman EA. Eckman CB, et al. Among authors: eckman ea. Neurol Clin. 2007 Aug;25(3):669-82, vi. doi: 10.1016/j.ncl.2007.03.007. Neurol Clin. 2007. PMID: 17659184 Free PMC article. Review.

6

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein.

Sambamurti K, Sevlever D, Koothan T, Refolo LM, Pinnix I, Gandhi S, Onstead L, Younkin L, Prada CM, Yager D, Ohyagi Y, Eckman CB, Rosenberry TL, Younkin SG. Sambamurti K, et al. Among authors: eckman cb. J Biol Chem. 1999 Sep 17;274(38):26810-4. doi: 10.1074/jbc.274.38.26810. J Biol Chem. 1999. PMID: 10480887 Free article.

7

Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease.

Golde TE, Eckman CB, Younkin SG. Golde TE, et al. Among authors: eckman cb. Biochim Biophys Acta. 2000 Jul 26;1502(1):172-87. doi: 10.1016/s0925-4439(00)00043-0. Biochim Biophys Acta. 2000. PMID: 10899442 Free article. Review.

8

Amyloid beta protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain.

Harigaya Y, Saido TC, Eckman CB, Prada CM, Shoji M, Younkin SG. Harigaya Y, et al. Among authors: eckman cb. Biochem Biophys Res Commun. 2000 Sep 24;276(2):422-7. doi: 10.1006/bbrc.2000.3490. Biochem Biophys Res Commun. 2000. PMID: 11027491

9

Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.

Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: eckman ea, eckman cb. FASEB J. 2001 Jan;15(1):16-18. doi: 10.1096/fj.00-0528fje. Epub 2000 Nov 9. FASEB J. 2001. PMID: 11099491

10

Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme.

Eckman EA, Reed DK, Eckman CB. Eckman EA, et al. Among authors: eckman cb. J Biol Chem. 2001 Jul 6;276(27):24540-8. doi: 10.1074/jbc.M007579200. Epub 2001 May 3. J Biol Chem. 2001. PMID: 11337485 Free article.

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