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Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities.
Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russell RG, Li M, Pestell RG, Di Vizio D, Hou H Jr, Kneitz B, Lagaud G, Christ GJ, Edelmann W, Lisanti MP. Razani B, et al. Among authors: di vizio d. J Biol Chem. 2001 Oct 12;276(41):38121-38. doi: 10.1074/jbc.M105408200. Epub 2001 Jul 16. J Biol Chem. 2001. PMID: 11457855 Free article.
Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice.
Williams TM, Hassan GS, Li J, Cohen AW, Medina F, Frank PG, Pestell RG, Di Vizio D, Loda M, Lisanti MP. Williams TM, et al. Among authors: di vizio d. J Biol Chem. 2005 Jul 1;280(26):25134-45. doi: 10.1074/jbc.M501186200. Epub 2005 Mar 30. J Biol Chem. 2005. PMID: 15802273 Free article.
p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling.
Hulit J, Lee RJ, Li Z, Wang C, Katiyar S, Yang J, Quong AA, Wu K, Albanese C, Russell R, Di Vizio D, Koff A, Thummala S, Zhang H, Harrell J, Sun H, Muller WJ, Inghirami G, Lisanti MP, Pestell RG. Hulit J, et al. Among authors: di vizio d. Cancer Res. 2006 Sep 1;66(17):8529-41. doi: 10.1158/0008-5472.CAN-06-0149. Cancer Res. 2006. PMID: 16951165
Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.
Williams TM, Sotgia F, Lee H, Hassan G, Di Vizio D, Bonuccelli G, Capozza F, Mercier I, Rui H, Pestell RG, Lisanti MP. Williams TM, et al. Among authors: di vizio d. Am J Pathol. 2006 Nov;169(5):1784-801. doi: 10.2353/ajpath.2006.060590. Am J Pathol. 2006. PMID: 17071600 Free PMC article.
The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
D'Amico M, Wu K, Di Vizio D, Reutens AT, Stahl M, Fu M, Albanese C, Russell RG, Muller WJ, White M, Negassa A, Lee HW, DePinho RA, Pestell RG. D'Amico M, et al. Among authors: di vizio d. Cancer Res. 2003 Jun 15;63(12):3395-402. Cancer Res. 2003. PMID: 12810676
139 results