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New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.
Plobeck N, Delorme D, Wei ZY, Yang H, Zhou F, Schwarz P, Gawell L, Gagnon H, Pelcman B, Schmidt R, Yue SY, Walpole C, Brown W, Zhou E, Labarre M, Payza K, St-Onge S, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Plobeck N, et al. Among authors: schmidt r. J Med Chem. 2000 Oct 19;43(21):3878-94. doi: 10.1021/jm000228x. J Med Chem. 2000. PMID: 11052793
N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: a novel, exceptionally selective, potent delta opioid receptor agonist with oral bioavailability and its analogues.
Wei ZY, Brown W, Takasaki B, Plobeck N, Delorme D, Zhou F, Yang H, Jones P, Gawell L, Gagnon H, Schmidt R, Yue SY, Walpole C, Payza K, St-Onge S, Labarre M, Godbout C, Jakob A, Butterworth J, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Wei ZY, et al. Among authors: schmidt r. J Med Chem. 2000 Oct 19;43(21):3895-905. doi: 10.1021/jm000229p. J Med Chem. 2000. PMID: 11052794
Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs.
Lembo PM, Grazzini E, Groblewski T, O'Donnell D, Roy MO, Zhang J, Hoffert C, Cao J, Schmidt R, Pelletier M, Labarre M, Gosselin M, Fortin Y, Banville D, Shen SH, Ström P, Payza K, Dray A, Walker P, Ahmad S. Lembo PM, et al. Among authors: schmidt r. Nat Neurosci. 2002 Mar;5(3):201-9. doi: 10.1038/nn815. Nat Neurosci. 2002. PMID: 11850634
Novel ligands lacking a positive charge for the delta- and mu-opioid receptors.
Schiller PW, Berezowska I, Nguyen TM, Schmidt R, Lemieux C, Chung NN, Falcone-Hindley ML, Yao W, Liu J, Iwama S, Smith AB 3rd, Hirschmann R. Schiller PW, et al. Among authors: schmidt r. J Med Chem. 2000 Feb 24;43(4):551-9. doi: 10.1021/jm990461z. J Med Chem. 2000. PMID: 10691681
6,264 results