Hadari YR - Search Results

1

Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways.

Hadari YR, Gotoh N, Kouhara H, Lax I, Schlessinger J. Hadari YR, et al. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8578-83. doi: 10.1073/pnas.161259898. Epub 2001 Jul 10. Proc Natl Acad Sci U S A. 2001. PMID: 11447289 Free PMC article.

2

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway.

Kouhara H, Hadari YR, Spivak-Kroizman T, Schilling J, Bar-Sagi D, Lax I, Schlessinger J. Kouhara H, et al. Among authors: hadari yr. Cell. 1997 May 30;89(5):693-702. doi: 10.1016/s0092-8674(00)80252-4. Cell. 1997. PMID: 9182757 Free article.

3

Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation.

Hadari YR, Kouhara H, Lax I, Schlessinger J. Hadari YR, et al. Mol Cell Biol. 1998 Jul;18(7):3966-73. doi: 10.1128/MCB.18.7.3966. Mol Cell Biol. 1998. PMID: 9632781 Free PMC article.

4

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins.

Ong SH, Hadari YR, Gotoh N, Guy GR, Schlessinger J, Lax I. Ong SH, et al. Among authors: hadari yr. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6074-9. doi: 10.1073/pnas.111114298. Epub 2001 May 15. Proc Natl Acad Sci U S A. 2001. PMID: 11353842 Free PMC article.

5

The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development.

Gotoh N, Manova K, Tanaka S, Murohashi M, Hadari Y, Lee A, Hamada Y, Hiroe T, Ito M, Kurihara T, Nakazato H, Shibuya M, Lax I, Lacy E, Schlessinger J. Gotoh N, et al. Mol Cell Biol. 2005 May;25(10):4105-16. doi: 10.1128/MCB.25.10.4105-4116.2005. Mol Cell Biol. 2005. PMID: 15870281 Free PMC article.

6

FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors.

Ong SH, Guy GR, Hadari YR, Laks S, Gotoh N, Schlessinger J, Lax I. Ong SH, et al. Among authors: hadari yr. Mol Cell Biol. 2000 Feb;20(3):979-89. doi: 10.1128/MCB.20.3.979-989.2000. Mol Cell Biol. 2000. PMID: 10629055 Free PMC article.

7

Docking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascade.

Melillo RM, Santoro M, Ong SH, Billaud M, Fusco A, Hadari YR, Schlessinger J, Lax I. Melillo RM, et al. Among authors: hadari yr. Mol Cell Biol. 2001 Jul;21(13):4177-87. doi: 10.1128/MCB.21.13.4177-4187.2001. Mol Cell Biol. 2001. PMID: 11390647 Free PMC article.

8

Distinct cellular properties of oncogenic KIT receptor tyrosine kinase mutants enable alternative courses of cancer cell inhibition.

Shi X, Sousa LP, Mandel-Bausch EM, Tome F, Reshetnyak AV, Hadari Y, Schlessinger J, Lax I. Shi X, et al. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4784-93. doi: 10.1073/pnas.1610179113. Epub 2016 Aug 1. Proc Natl Acad Sci U S A. 2016. PMID: 27482095 Free PMC article.

9

FGFR3-targeted mAb therapy for bladder cancer and multiple myeloma.

Hadari Y, Schlessinger J. Hadari Y, et al. J Clin Invest. 2009 May;119(5):1077-9. doi: 10.1172/jci38948. J Clin Invest. 2009. PMID: 19422094 Free PMC article.

10

Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration.

Lee S, Greenlee EB, Amick JR, Ligon GF, Lillquist JS, Natoli EJ Jr, Hadari Y, Alvarado D, Schlessinger J. Lee S, et al. Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13225-30. doi: 10.1073/pnas.1518361112. Epub 2015 Oct 12. Proc Natl Acad Sci U S A. 2015. PMID: 26460020 Free PMC article.

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