Eckman C - Search Results

1

Heritability of plasma amyloid beta in typical late-onset Alzheimer's disease pedigrees.

Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Adamson J, Schaid DJ, Blangero J, Hutton M, Younkin SG. Ertekin-Taner N, et al. Among authors: eckman c. Genet Epidemiol. 2001 Jul;21(1):19-30. doi: 10.1002/gepi.1015. Genet Epidemiol. 2001. PMID: 11443731

2

Amyloid beta protein starting pyroglutamate at position 3 is a major component of the amyloid deposits in the Alzheimer's disease brain.

Harigaya Y, Saido TC, Eckman CB, Prada CM, Shoji M, Younkin SG. Harigaya Y, et al. Among authors: eckman cb. Biochem Biophys Res Commun. 2000 Sep 24;276(2):422-7. doi: 10.1006/bbrc.2000.3490. Biochem Biophys Res Commun. 2000. PMID: 11027491

3

Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees.

Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG. Ertekin-Taner N, et al. Among authors: eckman c. Science. 2000 Dec 22;290(5500):2303-4. doi: 10.1126/science.290.5500.2303. Science. 2000. PMID: 11125143

4

Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease.

Golde TE, Eckman CB, Younkin SG. Golde TE, et al. Among authors: eckman cb. Biochim Biophys Acta. 2000 Jul 26;1502(1):172-87. doi: 10.1016/s0925-4439(00)00043-0. Biochim Biophys Acta. 2000. PMID: 10899442 Free article. Review.

5

A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43).

Eckman CB, Mehta ND, Crook R, Perez-tur J, Prihar G, Pfeiffer E, Graff-Radford N, Hinder P, Yager D, Zenk B, Refolo LM, Prada CM, Younkin SG, Hutton M, Hardy J. Eckman CB, et al. Hum Mol Genet. 1997 Nov;6(12):2087-9. doi: 10.1093/hmg/6.12.2087. Hum Mol Genet. 1997. PMID: 9328472

6

Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein.

Sambamurti K, Sevlever D, Koothan T, Refolo LM, Pinnix I, Gandhi S, Onstead L, Younkin L, Prada CM, Yager D, Ohyagi Y, Eckman CB, Rosenberry TL, Younkin SG. Sambamurti K, et al. Among authors: eckman cb. J Biol Chem. 1999 Sep 17;274(38):26810-4. doi: 10.1074/jbc.274.38.26810. J Biol Chem. 1999. PMID: 10480887 Free article.

7

Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin.

Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: eckman ea, eckman cb. FASEB J. 2001 Jan;15(1):16-18. doi: 10.1096/fj.00-0528fje. Epub 2000 Nov 9. FASEB J. 2001. PMID: 11099491

8

High throughput screens for the identification of compounds that alter the accumulation of the Alzheimer's amyloid beta peptide (Abeta).

Haugabook SJ, Yager DM, Eckman EA, Golde TE, Younkin SG, Eckman CB. Haugabook SJ, et al. Among authors: eckman ea, eckman cb. J Neurosci Methods. 2001 Jul 30;108(2):171-9. doi: 10.1016/s0165-0270(01)00388-0. J Neurosci Methods. 2001. PMID: 11478976

9

Increased Abeta42(43) from cell lines expressing presenilin 1 mutations.

Mehta ND, Refolo LM, Eckman C, Sanders S, Yager D, Perez-Tur J, Younkin S, Duff K, Hardy J, Hutton M. Mehta ND, et al. Among authors: eckman c. Ann Neurol. 1998 Feb;43(2):256-8. doi: 10.1002/ana.410430217. Ann Neurol. 1998. PMID: 9485068

10

Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells.

Refolo LM, Eckman C, Prada CM, Yager D, Sambamurti K, Mehta N, Hardy J, Younkin SG. Refolo LM, et al. Among authors: eckman c. J Neurochem. 1999 Dec;73(6):2383-8. doi: 10.1046/j.1471-4159.1999.0732383.x. J Neurochem. 1999. PMID: 10582597 Free article.

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