Borchelt DR - Search Results

1

Distinct behavioral and neuropathological abnormalities in transgenic mouse models of HD and DRPLA.

Schilling G, Jinnah HA, Gonzales V, Coonfield ML, Kim Y, Wood JD, Price DL, Li XJ, Jenkins N, Copeland N, Moran T, Ross CA, Borchelt DR. Schilling G, et al. Among authors: borchelt dr. Neurobiol Dis. 2001 Jun;8(3):405-18. doi: 10.1006/nbdi.2001.0385. Neurobiol Dis. 2001. PMID: 11442350

2

Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site.

Wang J, Xu G, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR. Wang J, et al. Among authors: borchelt dr. Neurobiol Dis. 2002 Jul;10(2):128-38. doi: 10.1006/nbdi.2002.0498. Neurobiol Dis. 2002. PMID: 12127151

3

Rapid detection of protein aggregates in the brains of Alzheimer patients and transgenic mouse models of amyloidosis.

Xu G, Gonzales V, Borchelt DR. Xu G, et al. Among authors: borchelt dr. Alzheimer Dis Assoc Disord. 2002 Jul-Sep;16(3):191-5. doi: 10.1097/00002093-200207000-00010. Alzheimer Dis Assoc Disord. 2002. PMID: 12218651

4

Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice.

Schilling G, Savonenko AV, Klevytska A, Morton JL, Tucker SM, Poirier M, Gale A, Chan N, Gonzales V, Slunt HH, Coonfield ML, Jenkins NA, Copeland NG, Ross CA, Borchelt DR. Schilling G, et al. Among authors: borchelt dr. Hum Mol Genet. 2004 Aug 1;13(15):1599-610. doi: 10.1093/hmg/ddh175. Epub 2004 Jun 9. Hum Mol Genet. 2004. PMID: 15190011

5

Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.

Wang J, Xu G, Slunt HH, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR. Wang J, et al. Among authors: borchelt dr. Neurobiol Dis. 2005 Dec;20(3):943-52. doi: 10.1016/j.nbd.2005.06.005. Epub 2005 Jul 19. Neurobiol Dis. 2005. PMID: 16046140

6

Progressive phenotype and nuclear accumulation of an amino-terminal cleavage fragment in a transgenic mouse model with inducible expression of full-length mutant huntingtin.

Tanaka Y, Igarashi S, Nakamura M, Gafni J, Torcassi C, Schilling G, Crippen D, Wood JD, Sawa A, Jenkins NA, Copeland NG, Borchelt DR, Ross CA, Ellerby LM. Tanaka Y, et al. Among authors: borchelt dr. Neurobiol Dis. 2006 Feb;21(2):381-91. doi: 10.1016/j.nbd.2005.07.014. Epub 2005 Sep 16. Neurobiol Dis. 2006. PMID: 16150600

7

Differential regulation of small heat shock proteins in transgenic mouse models of neurodegenerative diseases.

Wang J, Martin E, Gonzales V, Borchelt DR, Lee MK. Wang J, et al. Among authors: borchelt dr. Neurobiol Aging. 2008 Apr;29(4):586-97. doi: 10.1016/j.neurobiolaging.2006.11.009. Epub 2007 Feb 20. Neurobiol Aging. 2008. PMID: 17316906 Free PMC article.

8

Characterization of huntingtin pathologic fragments in human Huntington disease, transgenic mice, and cell models.

Schilling G, Klevytska A, Tebbenkamp AT, Juenemann K, Cooper J, Gonzales V, Slunt H, Poirer M, Ross CA, Borchelt DR. Schilling G, et al. Among authors: borchelt dr. J Neuropathol Exp Neurol. 2007 Apr;66(4):313-20. doi: 10.1097/nen.0b013e318040b2c8. J Neuropathol Exp Neurol. 2007. PMID: 17413322

9

Transgenic models of neurodegenerative diseases.

Lee MK, Borchelt DR, Wong PC, Sisodia SS, Price DL. Lee MK, et al. Among authors: borchelt dr. Curr Opin Neurobiol. 1996 Oct;6(5):651-60. doi: 10.1016/s0959-4388(96)80099-7. Curr Opin Neurobiol. 1996. PMID: 8937830 Free article. Review.

10

Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice.

Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. Borchelt DR, et al. Neurobiol Dis. 1998 Jul;5(1):27-35. doi: 10.1006/nbdi.1998.0178. Neurobiol Dis. 1998. PMID: 9702785 Free article.

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