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Page 1
Structural analysis of a set of proteins resulting from a bacterial genomics project.
Badger J, Sauder JM, Adams JM, Antonysamy S, Bain K, Bergseid MG, Buchanan SG, Buchanan MD, Batiyenko Y, Christopher JA, Emtage S, Eroshkina A, Feil I, Furlong EB, Gajiwala KS, Gao X, He D, Hendle J, Huber A, Hoda K, Kearins P, Kissinger C, Laubert B, Lewis HA, Lin J, Loomis K, Lorimer D, Louie G, Maletic M, Marsh CD, Miller I, Molinari J, Muller-Dieckmann HJ, Newman JM, Noland BW, Pagarigan B, Park F, Peat TS, Post KW, Radojicic S, Ramos A, Romero R, Rutter ME, Sanderson WE, Schwinn KD, Tresser J, Winhoven J, Wright TA, Wu L, Xu J, Harris TJ. Badger J, et al. Among authors: lewis ha. Proteins. 2005 Sep 1;60(4):787-96. doi: 10.1002/prot.20541. Proteins. 2005. PMID: 16021622
Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.
Lewis HA, Buchanan SG, Burley SK, Conners K, Dickey M, Dorwart M, Fowler R, Gao X, Guggino WB, Hendrickson WA, Hunt JF, Kearins MC, Lorimer D, Maloney PC, Post KW, Rajashankar KR, Rutter ME, Sauder JM, Shriver S, Thibodeau PH, Thomas PJ, Zhang M, Zhao X, Emtage S. Lewis HA, et al. EMBO J. 2004 Jan 28;23(2):282-93. doi: 10.1038/sj.emboj.7600040. Epub 2003 Dec 18. EMBO J. 2004. PMID: 14685259 Free PMC article.
Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure.
Lewis HA, Zhao X, Wang C, Sauder JM, Rooney I, Noland BW, Lorimer D, Kearins MC, Conners K, Condon B, Maloney PC, Guggino WB, Hunt JF, Emtage S. Lewis HA, et al. J Biol Chem. 2005 Jan 14;280(2):1346-53. doi: 10.1074/jbc.M410968200. Epub 2004 Nov 3. J Biol Chem. 2005. PMID: 15528182 Free article.
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Atwell S, Brouillette CG, Conners K, Emtage S, Gheyi T, Guggino WB, Hendle J, Hunt JF, Lewis HA, Lu F, Protasevich II, Rodgers LA, Romero R, Wasserman SR, Weber PC, Wetmore D, Zhang FF, Zhao X. Atwell S, et al. Among authors: lewis ha. Protein Eng Des Sel. 2010 May;23(5):375-84. doi: 10.1093/protein/gzq004. Epub 2010 Feb 11. Protein Eng Des Sel. 2010. PMID: 20150177
Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.
Ehrhardt A, Chung WJ, Pyle LC, Wang W, Nowotarski K, Mulvihill CM, Ramjeesingh M, Hong J, Velu SE, Lewis HA, Atwell S, Aller S, Bear CE, Lukacs GL, Kirk KL, Sorscher EJ. Ehrhardt A, et al. Among authors: lewis ha. J Biol Chem. 2016 Jan 22;291(4):1854-1865. doi: 10.1074/jbc.M115.704809. Epub 2015 Dec 1. J Biol Chem. 2016. PMID: 26627831 Free PMC article.
Structure-activity relationship (SAR) studies on substituted N-(pyridin-3-yl)-2-amino-isonicotinamides as highly potent and selective glycogen synthase kinase-3 (GSK-3) inhibitors.
Luo G, Chen L, Jacutin-Porte S, Han Y, Burton CR, Xiao H, Krause CM, Cao Y, Liu N, Kish K, Lewis HA, Macor JE, Dubowchik GM. Luo G, et al. Among authors: lewis ha. Bioorg Med Chem Lett. 2023 Feb 1;81:129143. doi: 10.1016/j.bmcl.2023.129143. Epub 2023 Jan 18. Bioorg Med Chem Lett. 2023. PMID: 36669575
69 results