Schwab M - Search Results

1

The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells.

Hitzl M, Drescher S, van der Kuip H, Schäffeler E, Fischer J, Schwab M, Eichelbaum M, Fromm MF. Hitzl M, et al. Among authors: schwab m. Pharmacogenetics. 2001 Jun;11(4):293-8. doi: 10.1097/00008571-200106000-00003. Pharmacogenetics. 2001. PMID: 11434506

2

Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6.

Raimundo S, Fischer J, Eichelbaum M, Griese EU, Schwab M, Zanger UM. Raimundo S, et al. Among authors: schwab m. Pharmacogenetics. 2000 Oct;10(7):577-81. doi: 10.1097/00008571-200010000-00001. Pharmacogenetics. 2000. PMID: 11037799

3

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver.

Lang T, Klein K, Fischer J, Nüssler AK, Neuhaus P, Hofmann U, Eichelbaum M, Schwab M, Zanger UM. Lang T, et al. Among authors: schwab m. Pharmacogenetics. 2001 Jul;11(5):399-415. doi: 10.1097/00008571-200107000-00004. Pharmacogenetics. 2001. PMID: 11470993

4

Comprehensive analysis of the genetic factors determining expression and function of hepatic CYP2D6.

Zanger UM, Fischer J, Raimundo S, Stüven T, Evert BO, Schwab M, Eichelbaum M. Zanger UM, et al. Among authors: schwab m. Pharmacogenetics. 2001 Oct;11(7):573-85. doi: 10.1097/00008571-200110000-00004. Pharmacogenetics. 2001. PMID: 11668217

5

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M, Schaeffeler E, Eichelbaum M, Brinkmann U, Roots I. Cascorbi I, et al. Among authors: schwab m. Clin Pharmacol Ther. 2001 Mar;69(3):169-74. doi: 10.1067/mcp.2001.114164. Clin Pharmacol Ther. 2001. PMID: 11240981 Clinical Trial.

6

Genetic influences on the pharmacokinetics of orally and intravenously administered digoxin as exhibited by monozygotic twins.

Birkenfeld AL, Jordan J, Hofmann U, Busjahn A, Franke G, Krüger N, Igel S, Mürdter T, Drescher S, Shi S, Engeli S, Schwab M, Eichelbaum M, Luft FC, Fromm MF. Birkenfeld AL, et al. Among authors: schwab m. Clin Pharmacol Ther. 2009 Dec;86(6):605-8. doi: 10.1038/clpt.2009.170. Epub 2009 Sep 23. Clin Pharmacol Ther. 2009. PMID: 19776737 Clinical Trial.

7

The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P glycoprotein) and consequences for the disposition of digoxin.

Burk O, Brenner SS, Hofmann U, Tegude H, Igel S, Schwab M, Eichelbaum M, Alscher MD. Burk O, et al. Among authors: schwab m. Clin Pharmacol Ther. 2010 Nov;88(5):685-94. doi: 10.1038/clpt.2010.176. Epub 2010 Sep 15. Clin Pharmacol Ther. 2010. PMID: 20844484

8

Frequency of C3435T polymorphism of MDR1 gene in African people.

Schaeffeler E, Eichelbaum M, Brinkmann U, Penger A, Asante-Poku S, Zanger UM, Schwab M. Schaeffeler E, et al. Among authors: schwab m. Lancet. 2001 Aug 4;358(9279):383-4. doi: 10.1016/S0140-6736(01)05579-9. Lancet. 2001. PMID: 11502320

9

High-throughput genotyping of thiopurine S-methyltransferase by denaturing HPLC.

Schaeffeler E, Lang T, Zanger UM, Eichelbaum M, Schwab M. Schaeffeler E, et al. Among authors: schwab m. Clin Chem. 2001 Mar;47(3):548-55. Clin Chem. 2001. PMID: 11238310

10

Variability in human hepatic MRP4 expression: influence of cholestasis and genotype.

Gradhand U, Lang T, Schaeffeler E, Glaeser H, Tegude H, Klein K, Fritz P, Jedlitschky G, Kroemer HK, Bachmakov I, Anwald B, Kerb R, Zanger UM, Eichelbaum M, Schwab M, Fromm MF. Gradhand U, et al. Among authors: schwab m. Pharmacogenomics J. 2008 Feb;8(1):42-52. doi: 10.1038/sj.tpj.6500451. Epub 2007 Apr 3. Pharmacogenomics J. 2008. PMID: 17404579

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