Dent P - Search Results

1

Pharmacological inhibitors of the mitogen-activated protein kinase (MAPK) kinase/MAPK cascade interact synergistically with UCN-01 to induce mitochondrial dysfunction and apoptosis in human leukemia cells.

Dai Y, Yu C, Singh V, Tang L, Wang Z, McInistry R, Dent P, Grant S. Dai Y, et al. Among authors: dent p. Cancer Res. 2001 Jul 1;61(13):5106-15. Cancer Res. 2001. PMID: 11431348

2

Pharmacologic mitogen-activated protein/extracellular signal-regulated kinase kinase/mitogen-activated protein kinase inhibitors interact synergistically with STI571 to induce apoptosis in Bcr/Abl-expressing human leukemia cells.

Yu C, Krystal G, Varticovksi L, McKinstry R, Rahmani M, Dent P, Grant S. Yu C, et al. Among authors: dent p. Cancer Res. 2002 Jan 1;62(1):188-99. Cancer Res. 2002. PMID: 11782377

3

Loss of the Bcl-2 phosphorylation loop domain is required to protect human myeloid leukemia cells from flavopiridol-mediated mitochondrial damage and apoptosis.

Decker RH, Wang S, Dai Y, Dent P, Grant S. Decker RH, et al. Among authors: dent p. Cancer Biol Ther. 2002 Mar-Apr;1(2):136-44. doi: 10.4161/cbt.58. Cancer Biol Ther. 2002. PMID: 12170773 Free article.

4

Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms.

Qiao L, Yacoub A, McKinstry R, Park JS, Caron R, Fisher PB, Hagan MP, Grant S, Dent P. Qiao L, et al. Among authors: dent p. Cancer Biol Ther. 2002 Mar-Apr;1(2):168-76. doi: 10.4161/cbt.64. Cancer Biol Ther. 2002. PMID: 12170777 Free article.

5

Flavopiridol potentiates STI571-induced mitochondrial damage and apoptosis in BCR-ABL-positive human leukemia cells.

Yu C, Krystal G, Dent P, Grant S. Yu C, et al. Among authors: dent p. Clin Cancer Res. 2002 Sep;8(9):2976-84. Clin Cancer Res. 2002. PMID: 12231544

6

Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism.

Dai Y, Landowski TH, Rosen ST, Dent P, Grant S. Dai Y, et al. Among authors: dent p. Blood. 2002 Nov 1;100(9):3333-43. doi: 10.1182/blood-2002-03-0940. Blood. 2002. PMID: 12384435 Free article.

7

Induction of apoptosis in human leukemia cells by the CDK1 inhibitor CGP74514A.

Dai Y, Dent P, Grant S. Dai Y, et al. Among authors: dent p. Cell Cycle. 2002 Mar-Apr;1(2):143-52. Cell Cycle. 2002. PMID: 12429924

8

Inhibitors of MEK1/2 interact with UCN-01 to induce apoptosis and reduce colony formation in mammary and prostate carcinoma cells.

McKinstry R, Qiao L, Yacoub A, Dai Y, Decker R, Holt S, Hagan MP, Grant S, Dent P. McKinstry R, et al. Among authors: dent p. Cancer Biol Ther. 2002 May-Jun;1(3):243-53. doi: 10.4161/cbt.75. Cancer Biol Ther. 2002. PMID: 12432271 Free article.

9

The role of signal transduction pathways in drug and radiation resistance.

Grant S, Fisher PB, Dent P. Grant S, et al. Among authors: dent p. Cancer Treat Res. 2002;112:89-108. doi: 10.1007/978-1-4615-1173-1_5. Cancer Treat Res. 2002. PMID: 12481713 Review. No abstract available.

10

Induction of tumor necrosis factor by bryostatin 1 is involved in synergistic interactions with paclitaxel in human myeloid leukemia cells.

Wang S, Wang Z, Dent P, Grant S. Wang S, et al. Among authors: dent p. Blood. 2003 May 1;101(9):3648-57. doi: 10.1182/blood-2002-09-2739. Epub 2003 Jan 9. Blood. 2003. PMID: 12522001 Free article.

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