Levitzki A - Search Results

1

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells.

Garcia R, Bowman TL, Niu G, Yu H, Minton S, Muro-Cacho CA, Cox CE, Falcone R, Fairclough R, Parsons S, Laudano A, Gazit A, Levitzki A, Kraker A, Jove R. Garcia R, et al. Among authors: levitzki a. Oncogene. 2001 May 3;20(20):2499-513. doi: 10.1038/sj.onc.1204349. Oncogene. 2001. PMID: 11420660

2

Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors.

Karni R, Jove R, Levitzki A. Karni R, et al. Among authors: levitzki a. Oncogene. 1999 Aug 19;18(33):4654-62. doi: 10.1038/sj.onc.1202835. Oncogene. 1999. PMID: 10467412

3

Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity.

Zhang Y, Turkson J, Carter-Su C, Smithgall T, Levitzki A, Kraker A, Krolewski JJ, Medveczky P, Jove R. Zhang Y, et al. Among authors: levitzki a. J Biol Chem. 2000 Aug 11;275(32):24935-44. doi: 10.1074/jbc.M002383200. J Biol Chem. 2000. PMID: 10823829 Free article.

4

Combination therapy with AG-490 and interleukin 12 achieves greater antitumor effects than either agent alone.

Burdelya L, Catlett-Falcone R, Levitzki A, Cheng F, Mora LB, Sotomayor E, Coppola D, Sun J, Sebti S, Dalton WS, Jove R, Yu H. Burdelya L, et al. Among authors: levitzki a. Mol Cancer Ther. 2002 Sep;1(11):893-9. Mol Cancer Ther. 2002. PMID: 12481410

5

Tyrosine kinase inhibition: an approach to drug development.

Levitzki A, Gazit A. Levitzki A, et al. Science. 1995 Mar 24;267(5205):1782-8. doi: 10.1126/science.7892601. Science. 1995. PMID: 7892601 Review.

6

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells.

Catlett-Falcone R, Landowski TH, Oshiro MM, Turkson J, Levitzki A, Savino R, Ciliberto G, Moscinski L, Fernández-Luna JL, Nuñez G, Dalton WS, Jove R. Catlett-Falcone R, et al. Among authors: levitzki a. Immunity. 1999 Jan;10(1):105-15. doi: 10.1016/s1074-7613(00)80011-4. Immunity. 1999. PMID: 10023775 Free article.

7

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases.

Nagane M, Levitzki A, Gazit A, Cavenee WK, Huang HJ. Nagane M, et al. Among authors: levitzki a. Proc Natl Acad Sci U S A. 1998 May 12;95(10):5724-9. doi: 10.1073/pnas.95.10.5724. Proc Natl Acad Sci U S A. 1998. PMID: 9576951 Free PMC article.

8

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor.

Schindler T, Sicheri F, Pico A, Gazit A, Levitzki A, Kuriyan J. Schindler T, et al. Among authors: levitzki a. Mol Cell. 1999 May;3(5):639-48. doi: 10.1016/s1097-2765(00)80357-3. Mol Cell. 1999. PMID: 10360180 Free article.

9

Development of new insulin-like growth factor-1 receptor kinase inhibitors using catechol mimics.

Blum G, Gazit A, Levitzki A. Blum G, et al. Among authors: levitzki a. J Biol Chem. 2003 Oct 17;278(42):40442-54. doi: 10.1074/jbc.M305490200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12869569 Free article.

Here we present a new family of bioisostere inhibitors, based on the structure of AG 538. AG 538 is a substrate-competitive inhibitor of the IGF-1 receptor (IGF-1R), with an IC50 = 61 nM in a cell-free kinase assay (Blum, G., Gazit, A., and Levitzki …

Here we present a new family of bioisostere inhibitors, based on the structure of AG 538. AG 538 is a substrate-competitive in …

10

Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors.

Gazit A, Yaish P, Gilon C, Levitzki A. Gazit A, et al. Among authors: levitzki a. J Med Chem. 1989 Oct;32(10):2344-52. doi: 10.1021/jm00130a020. J Med Chem. 1989. PMID: 2552117

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

341 results

Search Page

Filters