Ramsey TM - Search Results

1

A new Antennapedia-derived vector for intracellular delivery of exogenous compounds.

García-Echeverría C, Jiang L, Ramsey TM, Sharma SK, Chen YP. García-Echeverría C, et al. Among authors: ramsey tm. Bioorg Med Chem Lett. 2001 Jun 4;11(11):1363-6. doi: 10.1016/s0960-894x(01)00208-6. Bioorg Med Chem Lett. 2001. PMID: 11378355

2

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists.

Chen YN, Sharma SK, Ramsey TM, Jiang L, Martin MS, Baker K, Adams PD, Bair KW, Kaelin WG Jr. Chen YN, et al. Among authors: ramsey tm. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4325-9. doi: 10.1073/pnas.96.8.4325. Proc Natl Acad Sci U S A. 1999. PMID: 10200261 Free PMC article.

3

Identification of E2F-1/Cyclin A antagonists.

Sharma SK, Ramsey TM, Chen YN, Chen W, Martin MS, Clune K, Sabio M, Bair KW. Sharma SK, et al. Among authors: ramsey tm. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2449-52. doi: 10.1016/s0960-894x(01)00486-3. Bioorg Med Chem Lett. 2001. PMID: 11549444

4

Protein-protein interactions: lessons learned.

Sharma SK, Ramsey TM, Bair KW. Sharma SK, et al. Among authors: ramsey tm. Curr Med Chem Anticancer Agents. 2002 Mar;2(2):311-30. doi: 10.2174/1568011023354191. Curr Med Chem Anticancer Agents. 2002. PMID: 12678748 Review.

5

Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.

Shultz MD, Cao X, Chen CH, Cho YS, Davis NR, Eckman J, Fan J, Fekete A, Firestone B, Flynn J, Green J, Growney JD, Holmqvist M, Hsu M, Jansson D, Jiang L, Kwon P, Liu G, Lombardo F, Lu Q, Majumdar D, Meta C, Perez L, Pu M, Ramsey T, Remiszewski S, Skolnik S, Traebert M, Urban L, Uttamsingh V, Wang P, Whitebread S, Whitehead L, Yan-Neale Y, Yao YM, Zhou L, Atadja P. Shultz MD, et al. J Med Chem. 2011 Jul 14;54(13):4752-72. doi: 10.1021/jm200388e. Epub 2011 Jun 17. J Med Chem. 2011. PMID: 21650221

6

A Smac mimetic rescue screen reveals roles for inhibitor of apoptosis proteins in tumor necrosis factor-alpha signaling.

Gaither A, Porter D, Yao Y, Borawski J, Yang G, Donovan J, Sage D, Slisz J, Tran M, Straub C, Ramsey T, Iourgenko V, Huang A, Chen Y, Schlegel R, Labow M, Fawell S, Sellers WR, Zawel L. Gaither A, et al. Cancer Res. 2007 Dec 15;67(24):11493-8. doi: 10.1158/0008-5472.CAN-07-5173. Cancer Res. 2007. PMID: 18089776

7

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor.

Garcia Fortanet J, Chen CH, Chen YN, Chen Z, Deng Z, Firestone B, Fekkes P, Fodor M, Fortin PD, Fridrich C, Grunenfelder D, Ho S, Kang ZB, Karki R, Kato M, Keen N, LaBonte LR, Larrow J, Lenoir F, Liu G, Liu S, Lombardo F, Majumdar D, Meyer MJ, Palermo M, Perez L, Pu M, Ramsey T, Sellers WR, Shultz MD, Stams T, Towler C, Wang P, Williams SL, Zhang JH, LaMarche MJ. Garcia Fortanet J, et al. J Med Chem. 2016 Sep 8;59(17):7773-82. doi: 10.1021/acs.jmedchem.6b00680. Epub 2016 Jul 12. J Med Chem. 2016. PMID: 27347692

8

Synthesis of key analogs of bleomycin A2 that permit a systematic evaluation of the linker region: identification of an exceptionally prominent role for the L-threonine substituent.

Boger DL, Colletti SL, Teramoto S, Ramsey TM, Zhou J. Boger DL, et al. Among authors: ramsey tm. Bioorg Med Chem. 1995 Sep;3(9):1281-95. doi: 10.1016/0968-0896(95)00113-u. Bioorg Med Chem. 1995. PMID: 8564421

9

Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma.

Visser M, Papillon JPN, Luzzio M, LaMarche MJ, Fan J, Michael W, Wang D, Zhang A, Straub C, Mathieu S, Kato M, Palermo M, Chen C, Ramsey T, Joud C, Barrett R, Vattay A, Guo R, Bric A, Chung F, Liang G, Romanowski MJ, Lam J, Thohan S, Atassi F, Wylie A, Cooke VG. Visser M, et al. J Med Chem. 2024 Jan 25;67(2):1447-1459. doi: 10.1021/acs.jmedchem.3c02002. Epub 2024 Jan 10. J Med Chem. 2024. PMID: 38198520

10

AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma.

Sathornsumetee S, Hjelmeland AB, Keir ST, McLendon RE, Batt D, Ramsey T, Yusuff N, Rasheed BK, Kieran MW, Laforme A, Bigner DD, Friedman HS, Rich JN. Sathornsumetee S, et al. Cancer Res. 2006 Sep 1;66(17):8722-30. doi: 10.1158/0008-5472.CAN-06-0284. Cancer Res. 2006. PMID: 16951188

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