Cone RD - Search Results

1

Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants.

Haskell-Luevano C, Cone RD, Monck EK, Wan YP. Haskell-Luevano C, et al. Among authors: cone rd. Biochemistry. 2001 May 22;40(20):6164-79. doi: 10.1021/bi010025q. Biochemistry. 2001. PMID: 11352754

2

Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat.

Haskell-Luevano C, Chen P, Li C, Chang K, Smith MS, Cameron JL, Cone RD. Haskell-Luevano C, et al. Among authors: cone rd. Endocrinology. 1999 Mar;140(3):1408-15. doi: 10.1210/endo.140.3.6544. Endocrinology. 1999. PMID: 10067869

3

Altered expression of agouti-related protein and its colocalization with neuropeptide Y in the arcuate nucleus of the hypothalamus during lactation.

Chen P, Li C, Haskell-Luevano C, Cone RD, Smith MS. Chen P, et al. Among authors: cone rd. Endocrinology. 1999 Jun;140(6):2645-50. doi: 10.1210/endo.140.6.6829. Endocrinology. 1999. PMID: 10342854

4

Compounds that activate the mouse melanocortin-1 receptor identified by screening a small molecule library based upon the beta-turn.

Haskell-Luevano C, Rosenquist A, Souers A, Khong KC, Ellman JA, Cone RD. Haskell-Luevano C, et al. Among authors: cone rd. J Med Chem. 1999 Oct 21;42(21):4380-7. doi: 10.1021/jm990190s. J Med Chem. 1999. PMID: 10543881

5

Structure activity studies of the melanocortin antagonist SHU9119 modified at the 6, 7, 8, and 9 positions.

Haskell-Luevano C, Lim S, Yuan W, Cone RD, Hruby VJ. Haskell-Luevano C, et al. Among authors: cone rd. Peptides. 2000 Jan;21(1):49-57. doi: 10.1016/s0196-9781(99)00167-9. Peptides. 2000. PMID: 10704719

6

De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.

Han G, Haskell-Luevano C, Kendall L, Bonner G, Hadley ME, Cone RD, Hruby VJ. Han G, et al. Among authors: cone rd. J Med Chem. 2004 Mar 11;47(6):1514-26. doi: 10.1021/jm030452x. J Med Chem. 2004. PMID: 14998337

7

Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.

Hruby VJ, Lu D, Sharma SD, Castrucci AL, Kesterson RA, al-Obeidi FA, Hadley ME, Cone RD. Hruby VJ, et al. Among authors: cone rd. J Med Chem. 1995 Sep 1;38(18):3454-61. doi: 10.1021/jm00018a005. J Med Chem. 1995. PMID: 7658432

8

Role of melanocortinergic neurons in feeding and the agouti obesity syndrome.

Fan W, Boston BA, Kesterson RA, Hruby VJ, Cone RD. Fan W, et al. Among authors: cone rd. Nature. 1997 Jan 9;385(6612):165-8. doi: 10.1038/385165a0. Nature. 1997. PMID: 8990120

9

Expression of functional melanocortin-4 receptor in the hypothalamic GT1-1 cell line.

Khong K, Kurtz SE, Sykes RL, Cone RD. Khong K, et al. Among authors: cone rd. Neuroendocrinology. 2001 Sep;74(3):193-201. doi: 10.1159/000054686. Neuroendocrinology. 2001. PMID: 11528221

10

Studies on the physiological functions of the melanocortin system.

Cone RD. Cone RD. Endocr Rev. 2006 Dec;27(7):736-49. doi: 10.1210/er.2006-0034. Epub 2006 Oct 31. Endocr Rev. 2006. PMID: 17077189 Review.

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