Buchdunger E - Search Results

1

Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors.

Pietras K, Ostman A, Sjöquist M, Buchdunger E, Reed RK, Heldin CH, Rubin K. Pietras K, et al. Among authors: buchdunger e. Cancer Res. 2001 Apr 1;61(7):2929-34. Cancer Res. 2001. PMID: 11306470

2

Growth inhibition of dermatofibrosarcoma protuberans tumors by the platelet-derived growth factor receptor antagonist STI571 through induction of apoptosis.

Sjöblom T, Shimizu A, O'Brien KP, Pietras K, Dal Cin P, Buchdunger E, Dumanski JP, Ostman A, Heldin CH. Sjöblom T, et al. Among authors: buchdunger e. Cancer Res. 2001 Aug 1;61(15):5778-83. Cancer Res. 2001. PMID: 11479215

3

The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB.

Shimizu A, O'Brien KP, Sjöblom T, Pietras K, Buchdunger E, Collins VP, Heldin CH, Dumanski JP, Ostman A. Shimizu A, et al. Among authors: buchdunger e. Cancer Res. 1999 Aug 1;59(15):3719-23. Cancer Res. 1999. PMID: 10446987

4

Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy.

Pietras K, Rubin K, Sjöblom T, Buchdunger E, Sjöquist M, Heldin CH, Ostman A. Pietras K, et al. Among authors: buchdunger e. Cancer Res. 2002 Oct 1;62(19):5476-84. Cancer Res. 2002. PMID: 12359756

5

STI571 enhances the therapeutic index of epothilone B by a tumor-selective increase of drug uptake.

Pietras K, Stumm M, Hubert M, Buchdunger E, Rubin K, Heldin CH, McSheehy P, Wartmann M, Ostman A. Pietras K, et al. Among authors: buchdunger e. Clin Cancer Res. 2003 Sep 1;9(10 Pt 1):3779-87. Clin Cancer Res. 2003. PMID: 14506171

6

Oral imatinib mesylate (STI571/gleevec) improves the efficacy of local intravascular vascular endothelial growth factor-C gene transfer in reducing neointimal growth in hypercholesterolemic rabbits.

Leppänen O, Rutanen J, Hiltunen MO, Rissanen TT, Turunen MP, Sjöblom T, Brüggen J, Bäckström G, Carlsson M, Buchdunger E, Bergqvist D, Alitalo K, Heldin CH, Ostman A, Ylä-Herttuala S. Leppänen O, et al. Among authors: buchdunger e. Circulation. 2004 Mar 9;109(9):1140-6. doi: 10.1161/01.CIR.0000117234.08626.7C. Epub 2004 Feb 9. Circulation. 2004. PMID: 14769706

7

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

Bruns CJ, Solorzano CC, Harbison MT, Ozawa S, Tsan R, Fan D, Abbruzzese J, Traxler P, Buchdunger E, Radinsky R, Fidler IJ. Bruns CJ, et al. Among authors: buchdunger e. Cancer Res. 2000 Jun 1;60(11):2926-35. Cancer Res. 2000. PMID: 10850439

8

Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.

Kilic T, Alberta JA, Zdunek PR, Acar M, Iannarelli P, O'Reilly T, Buchdunger E, Black PM, Stiles CD. Kilic T, et al. Among authors: buchdunger e. Cancer Res. 2000 Sep 15;60(18):5143-50. Cancer Res. 2000. PMID: 11016641

9

Optimization for the blockade of epidermal growth factor receptor signaling for therapy of human pancreatic carcinoma.

Solorzano CC, Baker CH, Tsan R, Traxler P, Cohen P, Buchdunger E, Killion JJ, Fidler IJ. Solorzano CC, et al. Among authors: buchdunger e. Clin Cancer Res. 2001 Aug;7(8):2563-72. Clin Cancer Res. 2001. PMID: 11489840

10

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.

Wood JM, Bold G, Buchdunger E, Cozens R, Ferrari S, Frei J, Hofmann F, Mestan J, Mett H, O'Reilly T, Persohn E, Rösel J, Schnell C, Stover D, Theuer A, Towbin H, Wenger F, Woods-Cook K, Menrad A, Siemeister G, Schirner M, Thierauch KH, Schneider MR, Drevs J, Martiny-Baron G, Totzke F. Wood JM, et al. Among authors: buchdunger e. Cancer Res. 2000 Apr 15;60(8):2178-89. Cancer Res. 2000. PMID: 10786682

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