Alessi DR - Search Results

1

Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.

Sapkota GP, Kieloch A, Lizcano JM, Lain S, Arthur JS, Williams MR, Morrice N, Deak M, Alessi DR. Sapkota GP, et al. Among authors: alessi dr. J Biol Chem. 2001 Jun 1;276(22):19469-82. doi: 10.1074/jbc.M009953200. Epub 2001 Jan 31. J Biol Chem. 2001. PMID: 11297520 Free article.

2

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo.

Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR. Alessi DR, et al. J Biol Chem. 1995 Nov 17;270(46):27489-94. doi: 10.1074/jbc.270.46.27489. J Biol Chem. 1995. PMID: 7499206 Free article.

3

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B.

Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Cross DA, et al. Among authors: alessi dr. Nature. 1995 Dec 21-28;378(6559):785-9. doi: 10.1038/378785a0. Nature. 1995. PMID: 8524413

4

Mechanism of activation of protein kinase B by insulin and IGF-1.

Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA. Alessi DR, et al. EMBO J. 1996 Dec 2;15(23):6541-51. EMBO J. 1996. PMID: 8978681 Free PMC article.

5

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase.

Alessi DR, Caudwell FB, Andjelkovic M, Hemmings BA, Cohen P. Alessi DR, et al. FEBS Lett. 1996 Dec 16;399(3):333-8. doi: 10.1016/s0014-5793(96)01370-1. FEBS Lett. 1996. PMID: 8985174 Free article.

6

Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades.

Deprez J, Vertommen D, Alessi DR, Hue L, Rider MH. Deprez J, et al. Among authors: alessi dr. J Biol Chem. 1997 Jul 11;272(28):17269-75. doi: 10.1074/jbc.272.28.17269. J Biol Chem. 1997. PMID: 9211863 Free article.

7

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

Alessi DR, Deak M, Casamayor A, Caudwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A, Bownes M. Alessi DR, et al. Curr Biol. 1997 Oct 1;7(10):776-89. doi: 10.1016/s0960-9822(06)00336-8. Curr Biol. 1997. PMID: 9368760 Free article.

8

Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta.

Meier R, Alessi DR, Cron P, Andjelković M, Hemmings BA. Meier R, et al. Among authors: alessi dr. J Biol Chem. 1997 Nov 28;272(48):30491-7. doi: 10.1074/jbc.272.48.30491. J Biol Chem. 1997. PMID: 9374542 Free article.

9

Role of translocation in the activation and function of protein kinase B.

Andjelković M, Alessi DR, Meier R, Fernandez A, Lamb NJ, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA. Andjelković M, et al. Among authors: alessi dr. J Biol Chem. 1997 Dec 12;272(50):31515-24. doi: 10.1074/jbc.272.50.31515. J Biol Chem. 1997. PMID: 9395488 Free article.

10

3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.

Alessi DR, Kozlowski MT, Weng QP, Morrice N, Avruch J. Alessi DR, et al. Curr Biol. 1998 Jan 15;8(2):69-81. doi: 10.1016/s0960-9822(98)70037-5. Curr Biol. 1998. PMID: 9427642 Free article.

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